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在绵羊模型中,隧道缝合与缝线锚定方法随时间变化的比较。

Comparison of tunnel suture and suture anchor methods as a function of time in a sheep model.

作者信息

Lewis C W, Schlegel T F, Hawkins R J, James S P, Turner A S

机构信息

Mechanical Engineering, Colorado State University, Fort Collins, Colorado 80523-1374, USA.

出版信息

Biomed Sci Instrum. 1999;35:403-8.

PMID:11143386
Abstract

There is little quantitative information available on the required healing time after a rotator cuff surgery. This study evaluated two surgical procedures by comparing the healing strength as a function of time of the tendon in a bone trough using a sheep model. The two surgical procedures compared were bioabsorbable suture anchors and bone tunnel suture technique. The infraspinatus tendon was split in half and procedure (suture anchor/tunnel suture) locations were randomly allocated to the proximal or distal half of the tendon at the healing time points of 0, 3, 6, 9, and 12 weeks with n = 6 at t = 0 and n = 8 in all other groups. At each time point, the surgical (right) and normal (left) shoulders were harvested and stored in a -30 degrees C freezer until testing. Biomechanical testing was performed using a MTS 809 Axial/Torsional Servohydraulic System. Special cryo-grips designed and built to test the infraspinatus tendon-bone interface in anatomical alignment were used. All samples were preloaded with 5 Newtons, and then force was measured during a crosshead displacement of 50 cm/min until failure. Force and displacement data were recorded to calculate load to failure and stiffness of the bone-tendon construct. There was only significant difference (95% CI) in mean tensile force at week 0, with the bone tunnel suture technique tensile force greater than the suture anchor method tensile force (p = 0.0261). There was no significant difference between stiffness means at any of the survival times.

摘要

关于肩袖手术后所需的愈合时间,几乎没有定量信息。本研究使用绵羊模型,通过比较骨槽中肌腱愈合强度随时间的变化,评估了两种手术方法。所比较的两种手术方法是生物可吸收缝线锚钉和骨隧道缝合技术。在0、3、6、9和12周的愈合时间点,将冈下肌腱一分为二,并将手术方法(缝线锚钉/隧道缝合)位置随机分配到肌腱的近端或远端一半,t = 0时n = 6,其他所有组n = 8。在每个时间点,采集手术侧(右侧)和正常侧(左侧)肩部,并储存在-30℃的冰箱中直至测试。使用MTS 809轴向/扭转伺服液压系统进行生物力学测试。使用专门设计和制造的低温夹具,以解剖学对齐方式测试冈下肌腱-骨界面。所有样本先预加载5牛顿,然后在以50厘米/分钟的十字头位移过程中测量力,直至失效。记录力和位移数据,以计算骨-肌腱结构的失效载荷和刚度。仅在第0周平均拉力存在显著差异(95%置信区间),骨隧道缝合技术的拉力大于缝线锚钉方法的拉力(p = 0.0261)。在任何存活时间的刚度平均值之间均无显著差异。

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