Carol W, Kluge K, Hempel E, Klinger G
Zentralbl Gynakol. 1979;101(8):497-501.
Use of the antiandrogen cyproterone acetate in the treatment of hirsutism.--25 women with hirsutism or hypertrichosis faciei were subject to a "reverse sequential therapy" with cyproterone acetate (Hammerstein's regimen) for 1 to 3 years. In 8 patients, a limited, in 14 patients a satisfactory and in one woman a good result could be recorded. Cycle irregularities and subjective side effects were within a tolerable range. Studies of the hair pattern in 15 patients revealed a higher telogen rate as well as increased diameters of the hair stalks, compared with controls, in the temporal region of the head. These alterations disappeared in the course of the treatment. In the parietal region of the head no significant differences of the hair pattern were found in comparison with the controls and during application of the steroids.
使用抗雄激素醋酸环丙孕酮治疗多毛症。——25名患有多毛症或面部多毛的女性接受了醋酸环丙孕酮的“反向序贯疗法”（哈默斯坦疗法），为期1至3年。8名患者效果有限，14名患者效果满意，1名女性效果良好。月经周期不规律和主观副作用在可耐受范围内。对15名患者毛发模式的研究显示，与对照组相比，头部颞部的休止期毛发比例更高，毛干直径也更大。这些改变在治疗过程中消失。与对照组相比以及在使用类固醇期间，头部顶叶区域的毛发模式没有显著差异。
