Rafael H, Mego R, Moromizato P, Espinoza M
Departments of Neurosurgery, General Surgery and Anesthesiology, Universidad Nacional Autonoma deMexico(UNAM), Mexico City, Mexico.
Neurol India. 2000 Dec;48(4):319-21.
The acetylcholine, dopamine, serotonin and other neurotransmitters may be reduced in the subcommissural regions even in the early stages of Alzheimer's disease(AD), due to hypoperfusion of the anterior perforating and anterior choroidal arteries. This hypothesis was confirmed after the transplant of omental tissue on the optic chiasma, carotid crotch and anterior perforated space in a woman with moderate AD. Neurological improvement was better in the first week after the surgery than in the following months.
即使在阿尔茨海默病(AD)的早期阶段,由于前穿动脉和脉络膜前动脉灌注不足,连合下区域的乙酰胆碱、多巴胺、5-羟色胺和其他神经递质可能会减少。在一名中度AD女性患者的视交叉、颈动脉分叉和前穿质间隙移植网膜组织后,这一假说得到了证实。术后第一周的神经功能改善比接下来的几个月更好。