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三名老年食管癌患者通过纵隔镜辅助经裂孔食管切除术成功治愈。

Three elderly patients with lower esophageal cancer successfully treated by transhiatal esophagectomy assisted by mediastinoscopy.

作者信息

Koide N, Hiraguri M, Nishio A, Igarashi J, Watanabe H, Adachi W, Amano J

机构信息

Second Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.

出版信息

Surg Laparosc Endosc Percutan Tech. 2000 Dec;10(6):391-5.

PMID:11147916
Abstract

Mediastinoscopy-assisted transhiatal esophagectomy recently has been applied in patients with intrathoracic esophageal cancer. Elderly patients with esophageal cancer experience several types of complications and often cannot undergo standard transthoracic esophagectomy. In this study, three elderly patients with preoperative complications underwent mediastinoscopy-assisted transhiatal esophagectomy for esophageal cancer located in the lower part of the esophagus. Patient 1 was an 80-year-old man with alcoholic liver cirrhosis. Patient 2 was a 78-year-old man with bronchial asthma. Patient 3 was an 81-year-old-man with diabetes mellitus and an atherosclerotic obstruction of the lower extremities. In these patients, mediastinoscopy-assisted transhiatal esophagectomy concomitant with reconstruction by means of a gastric tube was performed. Lymph node dissections of the middle and lower mediastinum and of the abdomen, including the regions surrounding the left gastric and celiac arteries, were performed. Postoperative complications developed only in patient 1; minor leakage of the esophagogastrostomy and high bilirubinemia were observed. Metastasis was detected in the lymph nodes surrounding the celiac artery in patient 1 and surrounding the left gastric artery in patients 2 and 3. Patient 2 died of pneumonia 18 months later, but the other patients have been well, without recurrence of the cancer after surgery. In conclusion, mediastinoscopy-assisted transhiatal esophagectomy has some benefits for elderly esophageal cancer patients who experience preoperative complications.

摘要

纵隔镜辅助经裂孔食管切除术最近已应用于胸段食管癌患者。老年食管癌患者会出现多种并发症,往往无法接受标准的经胸食管切除术。在本研究中,3例术前有并发症的老年患者接受了纵隔镜辅助经裂孔食管切除术,治疗位于食管下段的食管癌。患者1是一名80岁男性,患有酒精性肝硬化。患者2是一名78岁男性,患有支气管哮喘。患者3是一名81岁男性,患有糖尿病和下肢动脉粥样硬化梗阻。对这些患者实施了纵隔镜辅助经裂孔食管切除术并同时用胃管进行重建。进行了纵隔中下部及腹部的淋巴结清扫,包括胃左动脉和腹腔动脉周围区域。术后并发症仅发生在患者1;观察到食管胃吻合口轻微渗漏和高胆红素血症。在患者1的腹腔动脉周围淋巴结以及患者2和3的胃左动脉周围检测到转移。患者2在18个月后死于肺炎,但其他患者情况良好,术后无癌症复发。总之,纵隔镜辅助经裂孔食管切除术对有术前并发症的老年食管癌患者有一定益处。

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Three elderly patients with lower esophageal cancer successfully treated by transhiatal esophagectomy assisted by mediastinoscopy.三名老年食管癌患者通过纵隔镜辅助经裂孔食管切除术成功治愈。
Surg Laparosc Endosc Percutan Tech. 2000 Dec;10(6):391-5.
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Effectiveness of radical en-bloc-esophagectomy compared to transhiatal esophagectomy in squamous cell cancer of the esophagus is influenced by nodal micrometastases.与经胸食管切除术相比,根治性整块食管切除术治疗食管鳞状细胞癌的疗效受淋巴结微转移的影响。
J Surg Oncol. 2006 Jun 1;93(7):541-9. doi: 10.1002/jso.20544.

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Application of Inflatable Video-Assisted Mediastinoscopic Transhiatal Esophagectomy in Individualized Treatment of Esophageal Cancer.充气式电视辅助纵隔镜经裂孔食管癌切除术在食管癌个体化治疗中的应用
Biomedicines. 2023 Oct 11;11(10):2750. doi: 10.3390/biomedicines11102750.
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Mediastinoscopy-assisted esophagectomy for esophageal cancer in patients with serious comorbidities.胸腔镜辅助食管癌切除术治疗合并严重合并症的食管癌患者。
Surg Today. 2012 Jan;42(2):127-34. doi: 10.1007/s00595-011-0042-3. Epub 2011 Nov 10.