Qureshi Ahmad Uzair, Iqbal Munazza, Gondal Khalid Masud
Department of Surgery, Mayo Hospital, Lahore.
J Coll Physicians Surg Pak. 2009 Jul;19(7):413-6.
The aim of this study was to determine the outcomes of transhiatal esophagectomy for dysphagia for esophageal malignancy in terms of short and long-term morbidity and mortality and to determine the survival series.
Case series study.
South and West Surgical Ward, Mayo Hospital, Lahore, from January 2001 to December 2007.
All patients referred electively or admitted through OPD presenting with features of progressive dysphagia due to malignancy were included in the study. The patients were investigated for site of stricture and extent of growth into the surrounding structures. All underwent transhiatal esophagectomy and gastric tube or colon was used as the conduit to restore continuity. Patients with squamous cell variety were referred to oncology department for chemoradiotherapy postoperatively. Morbidity and in-hospital mortality were recorded.
A total of 42 patients were operated electively for malignant stricture esophagus through transhiatal approach. Site of lesion were 5 (11.9%) upper, 13 (31%) middle and 24 (58%) at lower end of esophagus. The TNM staging were stage I, IIa, IIb, III and IV in zero (0), 5 (11%), 10 (22%), 24 (57.8%) and 3 (7.1%) respectively. Mean operating time was 154 minutes and average blood loss of 371 ml. Postoperative complications included pneumothorax 16.7%, pulmonary complication (16.7%), anastomotic leakage (9.5%), wound infection (3.4%), recurrent laryngeal nerve injury (4.8%) and stricture formation (4.8%). Only 3 (7.1%) 30-day in-hospital mortality was recorded.
Transhiatal esophagectomy is the surgical treatment of choice for resection of carcinoma esophagus specifically at the lower and mid-esophageal levels. The frequency of complications is lower as compared to transthoracic approach and the early stage of presentation can lead to high 5-year survival ratios.
本研究旨在确定经胸食管切除术治疗食管恶性肿瘤所致吞咽困难的短期和长期发病率及死亡率,并确定生存情况。
病例系列研究。
2001年1月至2007年12月,拉合尔梅奥医院的南部和西部外科病房。
所有因恶性肿瘤导致进行性吞咽困难而被选择性转诊或通过门诊入院的患者均纳入研究。对患者进行狭窄部位及肿瘤向周围结构生长范围的检查。所有患者均接受经胸食管切除术,并使用胃管或结肠作为恢复连续性的管道。鳞状细胞癌患者术后被转至肿瘤科进行放化疗。记录发病率和住院死亡率。
共有42例患者通过经胸途径接受了食管恶性狭窄的选择性手术。病变部位为食管上段5例(11.9%)、中段13例(31%)、下段24例(58%)。TNM分期分别为I期0例(0%)、IIa期5例(11%)、IIb期10例(22%)、III期24例(57.8%)、IV期3例(7.1%)。平均手术时间为154分钟,平均失血量为371毫升。术后并发症包括气胸16.7%、肺部并发症(16.7%)、吻合口漏(9.5%)、伤口感染(3.4%)、喉返神经损伤(4.8%)和狭窄形成(4.8%)。仅记录到3例(7.1%)30天住院死亡率。
经胸食管切除术是食管下段和中段癌切除术的首选手术治疗方法。与经胸手术相比,并发症发生率较低,早期就诊可导致较高的5年生存率。