Dupuis-Girod S, Gluckman E, Souberbielle J C, Brauner R
Pediatric Endocrinology and Immuno-Hematology Departments, Physiology Laboratory, Université René Descartes and Hôpital Necker-Enfants Malades, Paris, France.
J Pediatr. 2001 Jan;138(1):129-33. doi: 10.1067/mpd.2001.109200.
Fanconi's anemia can be associated with growth retardation. We describe biologic growth hormone deficiency, isolated or associated with thyrotropin abnormality, and pituitary stalk interruption syndrome on magnetic resonance imaging of 5 patients with Fanconi's anemia. Growth hormone treatment produced catch-up growth in all cases. These findings suggest a common genetic origin.
范科尼贫血可能与生长发育迟缓有关。我们描述了5例范科尼贫血患者的生物学生长激素缺乏症，可为孤立性或伴有促甲状腺激素异常，以及磁共振成像显示的垂体柄中断综合征。生长激素治疗在所有病例中均产生了追赶生长。这些发现提示存在共同的遗传起源。
