Taoka Toshiaki, Iwasaki Satoru, Okamoto Shingo, Sakamoto Masahiko, Nakagawa Hiroyuki, Otake Shoichiro, Fujioka Masayuki, Hirohashi Shinji, Kichikawa Kimihiko
Department of Radiology, Nara Medical University, Nara 634-8522, Japan.
Magn Reson Imaging. 2006 Jun;24(5):651-6. doi: 10.1016/j.mri.2005.12.015. Epub 2006 Feb 20.
The purpose of this study was to evaluate the relationship between pituitary stalk compression by the dorsum sellae and clinical or laboratory findings in short stature children.
We retrospectively reviewed magnetic resonance images of the pituitary gland and pituitary stalk for 34 short stature children with growth hormone (GH) deficiency and 24 age-matched control cases. We evaluated the degree of pituitary stalk compression caused by the dorsum sellae. Body height, GH level, pituitary height and onset age of the short stature were statistically compared between cases of pituitary stalk compression with associated stalk deformity and cases without compression.
Compression of the pituitary stalk with associated stalk deformity was seen in nine cases within the short stature group. There were no cases observed in the control group. There were no significant differences found for body height, GH level and pituitary height between the cases of pituitary stalk compression with associated stalk deformity and cases without compression. However, a significant difference was seen in the onset age between cases with and without stalk compression.
Pituitary stalk compression with stalk deformity caused by the dorsum sellae was significantly correlated with late childhood onset of short stature.
本研究旨在评估蝶鞍背对垂体柄的压迫与身材矮小儿童临床或实验室检查结果之间的关系。
我们回顾性分析了34例生长激素（GH）缺乏的身材矮小儿童及24例年龄匹配的对照病例的垂体和垂体柄磁共振成像。我们评估了蝶鞍背对垂体柄的压迫程度。对伴有垂体柄畸形的垂体柄受压病例与无受压病例的身高、GH水平、垂体高度及身材矮小发病年龄进行了统计学比较。
身材矮小组中有9例出现伴有垂体柄畸形的垂体柄受压情况。对照组未观察到此类病例。伴有垂体柄畸形的垂体柄受压病例与无受压病例在身高、GH水平和垂体高度方面未发现显著差异。然而，有、无垂体柄受压病例的发病年龄存在显著差异。
蝶鞍背引起的伴有垂体柄畸形的垂体柄受压与儿童期晚期身材矮小发病显著相关。
