Sofer M, Denstedt J D
Division of Urology, The University of Western Ontario, London, Canada.
Curr Opin Urol. 2000 Nov;10(6):563-9. doi: 10.1097/00042307-200011000-00005.
The present review focuses on technological advances and relevant research related to encrustation of biomaterials in the urinary tract. The importance of physical and chemical biomaterial type, biocompatibility, material coatings such as hydrogels, and infection related to alloplastic materials used in urological practice are discussed. Recent in-vitro and in-vivo research has focused on materials that will reduce encrustation and bacterial biofilm formation, complications that limit the long-term use of urinary materials. Coordinating scientific resources in a multidisciplinary manner for a better understanding of factors that are involved in encrustation and biofilm formation will offer the potential to modify or resolve the problem of encrustation of foreign materials in the urinary tract.
本综述聚焦于与尿路生物材料结壳相关的技术进展及相关研究。讨论了物理和化学生物材料类型、生物相容性、诸如水凝胶等材料涂层以及泌尿外科实践中使用的异体材料相关感染的重要性。近期的体外和体内研究集中于能减少结壳和细菌生物膜形成的材料，这些并发症限制了泌尿材料的长期使用。以多学科方式协调科学资源，以更好地理解参与结壳和生物膜形成的因素，将为改变或解决尿路中异物结壳问题提供可能性。
