Bishop M C
Department of Urology, Nottingham City Hospital, Nottingham, UK.
Curr Opin Urol. 2001 Jan;11(1):67-73. doi: 10.1097/00042307-200101000-00010.
Infection within the abdominal wall and peritonitis are still important causes of morbidity which ultimately limit the use of peritoneal dialysis in end-stage renal failure. Similarly disastrous complications resulting in loss of access can follow infection in venous cannulae and artificial arteriovenous fistulae, particularly in synthetic vascular grafts. Important publications continue to underline the mechanism of reduced resistance to infection by uraemic patients. After renal transplantation bacterial infection is common and predictable. However, immunosuppressed recipients are particularly susceptible to viral and fungal infection. Arguably infection of all types can induce organ rejection.
腹壁感染和腹膜炎仍是导致发病的重要原因,最终限制了腹膜透析在终末期肾衰竭中的应用。同样,静脉插管和人工动静脉瘘感染,尤其是合成血管移植物感染,可能引发灾难性并发症,导致通路丧失。重要出版物不断强调尿毒症患者抗感染能力下降的机制。肾移植后细菌感染很常见且可预测。然而,免疫抑制的受者特别容易发生病毒和真菌感染。可以说,所有类型的感染都可能诱发器官排斥反应。