Hammett T M, Norton G D, Mason T H, Langenbahn S, Mayer K H, Robles R R, Feudo R, Seage G R
Abt Associates Inc., Cambridge, Massachusetts 02138-1168, USA.
J Womens Health Gend Based Med. 2000 Dec;9(10):1071-80. doi: 10.1089/152460900445983.
We wished to obtain potential users' perspectives on vaginal microbicides from a population of women at high risk for HIV. We conducted a face-to-face survey of convenience samples (total n = 743) of drug-using women and female sexual partners of male injection drug users in Bridgeport, Connecticut, Providence, Rhode Island, and San Juan, Puerto Rico. Ninety percent of respondents said that they would be very likely to use microbicides with paying partners and 78% with primary partners (p = 0.001). High hypothetical likelihood of use was expressed even after several potential product characteristics (e.g., causes minor vaginal irritation or burning) were rated as unacceptable. Latinas had significantly higher predicted likelihood of use with primary (p = 0. 001) and paying partners (p = 0.018) than blacks and whites. Eighty percent of respondents preferred products that enhance sexual pleasure by providing additional lubrication or "wetness." More than 80% of respondents said that they would want their primary partners to know of their microbicide use, and 42% (p = 0.001) said that they would want their paying partners to know. Women's concern about a paying partner's violent response to suggested use of risk reduction measures was inversely related to predicted likelihood of microbicide use (p = 0.045). Microbicides should be assessed in the context of the potential users' actual relationships and cultures. Achieving broad acceptability among drug-involved women will require a range of products.
我们希望从感染艾滋病毒风险较高的女性群体中获取她们对阴道杀微生物剂的潜在用户观点。我们对康涅狄格州布里奇波特、罗德岛州普罗维登斯和波多黎各圣胡安的吸毒女性以及男性注射吸毒者的女性性伴侣进行了便利抽样的面对面调查（样本总数n = 743）。90%的受访者表示，她们很可能会与付费伴侣使用杀微生物剂，78%的受访者表示会与主要伴侣使用（p = 0.001）。即使在几种潜在产品特性（如引起轻微阴道刺激或灼烧感）被评为不可接受之后，仍有较高的假设使用可能性。拉丁裔女性与主要伴侣（p = 0.001）和付费伴侣（p = 0.018）使用杀微生物剂的预测可能性显著高于黑人和白人。80%的受访者更喜欢通过提供额外润滑或“湿润感”来增强性快感的产品。超过80%的受访者表示，她们希望主要伴侣知道她们使用杀微生物剂，42%（p = 0.001）的受访者表示希望付费伴侣知道。女性担心付费伴侣对建议使用风险降低措施的暴力反应与杀微生物剂使用的预测可能性呈负相关（p = 0.045）。应在潜在用户的实际关系和文化背景下评估杀微生物剂。要在涉毒女性中实现广泛接受，将需要一系列产品。
