Young P J, Burchett K, Harvey I, Blunt M C
Intensive Care Unit, Queen Elizabeth Hospital, King's Lynn, United Kingdom.
Anaesth Intensive Care. 2000 Dec;28(6):660-5. doi: 10.1177/0310057X0002800609.
A prospective open randomized controlled study was performed to assess the ability of Euromedical ILM endotracheal tube cuff (silicone cuff) to prevent pulmonary aspiration. The inflation characteristics of this silicone cuff enables the control of tracheal wall pressure. The silicone cuffed tube was shortened and an adjustable flange was used to convert it to a cuffed tracheostomy tube. Twelve patients requiring a tracheostomy on a four-bed intensive care unit (ICU) in a district general hospital received either a silicone or a Shiley cuffed tracheostomy tube. Tracheal wall pressures of both cuffs were maintained at 30 cm H2O with a constant pressure inflation device. Blue food dye was instilled once daily into the subglottic space through a fine catheter above the cuff. There were six patients in the Shiley group and six patients in the silicone cuff group. Dye leaked to the trachea in six (100%) of the Shiley group compared with none (0%) of the silicone cuff group (P = 0.001). This study confirms the effectiveness of this silicone cuff at preventing aspiration and the high incidence of leakage with the conventional high-volume low-pressure tracheostomy tube cuff.
进行了一项前瞻性开放性随机对照研究，以评估欧罗医疗ILM气管导管套囊（硅胶套囊）预防肺误吸的能力。这种硅胶套囊的充气特性能够控制气管壁压力。将硅胶带套囊导管缩短，并使用可调节凸缘将其转换为带套囊的气管造口术导管。在一家地区综合医院的四床重症监护病房（ICU）中，12名需要进行气管造口术的患者分别接受了硅胶或Shiley带套囊气管造口术导管。使用恒压充气装置将两个套囊的气管壁压力维持在30 cm H₂O。每天通过套囊上方的细导管向声门下间隙注入一次蓝色食用染料。Shiley组和硅胶套囊组各有6名患者。Shiley组中有6例（100%）染料漏入气管，而硅胶套囊组无一例（0%）发生染料漏入气管的情况（P = 0.001）。本研究证实了这种硅胶套囊在预防误吸方面的有效性，以及传统大容量低压气管造口术导管套囊的高渗漏发生率。
