Martinek V, Seil R, Lattermann C, Watkins S C, Fu F H
Department of Orthopaedic Surgery, and the Center for Biologic Imaging,The University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Arthroscopy. 2001 Jan;17(1):73-6. doi: 10.1053/jars.2001.7797.
We report the persistence of a poly-L-lactic acid (PLLA) interference screw 2.5 years after anterior cruciate ligament (ACL) reconstruction with Achilles tendon allograft. The arthroscopy was performed because the patient sustained a reinjury of the ACL graft, making ACL revision surgery necessary. At the time of arthroscopy, both PLLA screws were macroscopically still intact but could not be removed in 1 piece. No inflammation could be observed either macroscopically or in the histologic analysis. The biopsy specimen from the femoral insertion of the graft showed parts of the PLLA material surrounded by scar tissue. This case shows that biodegradation of PLLA material in the knee joint causes no irritation and can take several years, even if the material is in contact with the synovial fluid.
我们报告了在使用跟腱同种异体移植物进行前交叉韧带(ACL)重建术后2.5年,聚-L-乳酸(PLLA)干涉螺钉持续存在的情况。进行关节镜检查是因为患者ACL移植物再次受伤,使得ACL翻修手术成为必要。在关节镜检查时,两个PLLA螺钉在宏观上仍然完好无损,但无法完整取出。无论是在宏观上还是在组织学分析中,均未观察到炎症。来自移植物股骨附着点的活检标本显示,PLLA材料的部分被瘢痕组织包围。该病例表明,即使PLLA材料与滑液接触,其在膝关节内的生物降解也不会引起刺激,并且可能需要数年时间。