Contreras A, Doan N, Chen C, Rusitanonta T, Flynn M J, Slots J
Department of Periodontology, School of Dentistry, University of Southern California, Los Angeles, CA 90089-0641, USA.
Oral Microbiol Immunol. 2000 Aug;15(4):269-72. doi: 10.1034/j.1399-302x.2000.150410.x.
Anaerobic bacteria play important roles in the pathogenesis of human periodontitis. This study examined the relationship between a potentially new periodontopathic bacterium Dialister pneumosintes and periodontal disease. A total of 73 women and 62 men aged 18 to 86 years participated in the study. Using a 16S rRNA polymerase chain reaction identification method, the presence of D. pneumosintes was determined in paper-point samples from periodontal pockets of 105 periodontitis and 30 gingivitis patients. D. pneumosintes was detected in 83% of patients having severe periodontitis and in 19% of patients having slight periodontitis. We suggest adding D. pneumosintes to the group of suspected periodontal pathogens.
厌氧菌在人类牙周炎的发病机制中起重要作用。本研究检测了一种潜在的新型牙周病原菌——肺炎戴阿李斯特菌与牙周疾病之间的关系。共有18至86岁的73名女性和62名男性参与了该研究。采用16S rRNA聚合酶链反应鉴定方法,在105例牙周炎患者和30例牙龈炎患者牙周袋的纸尖样本中检测肺炎戴阿李斯特菌的存在。在重度牙周炎患者中有83%检测到肺炎戴阿李斯特菌,在轻度牙周炎患者中有19%检测到该菌。我们建议将肺炎戴阿李斯特菌纳入可疑牙周病原体组。