Emmons P R, Blume W T, DuShane J W
Arch Neurol. 1975 Jan;32(1):59-61. doi: 10.1001/archneur.1975.00490430081017.
Life-threatening alterations of respiratory and cardiovascular functions may complicate the course of severe Guillain-Barre syndrome. Cardiac arrest, fore-warned by episodes of bradycardia or other arrhythmia, may occur despite adequately assisted respirations. A patient with Guillain-Barre syndrome required tracheostomy and ventilatory assistance. Continuous cardiac monitoring revealed that tracheal aspiration provoked an idioventricular rhythm of 40 beats per minute, which reverted to sinus rhythm after the procedure. To prevent cardiac arrest during the transition from idioventricular to sinus rhythm, a demand pacemaker was inserted into the right ventricle. Set to activate if the rate fell below 65 beats per minute, the pacemaker functioned both during and between tracheal aspiration procedures. Cardiac monitoring in severe cases of Guillain-Barre syndrome may detect potentially lethal arrhythmias that may then be avoided by a demand pacemaker.
危及生命的呼吸和心血管功能改变可能使严重吉兰-巴雷综合征的病程复杂化。尽管进行了充分的辅助呼吸,但仍可能发生由心动过缓或其他心律失常发作预先警示的心脏骤停。一名吉兰-巴雷综合征患者需要气管切开术和通气辅助。持续心脏监测显示,气管吸引诱发了每分钟40次的室性自主心律,术后恢复为窦性心律。为防止在从室性自主心律转变为窦性心律期间发生心脏骤停,在右心室植入了按需起搏器。设定为心率低于每分钟65次时激活,该起搏器在气管吸引操作期间和操作之间均发挥作用。对严重吉兰-巴雷综合征病例进行心脏监测可能会检测到潜在致命的心律失常,然后可通过按需起搏器避免这种情况。