Ashton C H
University of Newcastle upon Tyne, Department of Psychiatry, Royal Victoria Infirmary, Newcastle upon Tyne NEI 4LP, UK.
Br J Psychiatry. 2001 Feb;178:101-6. doi: 10.1192/bjp.178.2.101.
Increasing prevalence of recreational cannabis use among the young population has stimulated debate on the possible effects of acute and longterm use.
To highlight recent knowledge of mechanisms of action, effects on psychomotor and cognitive performance, and health risks associated with cannabis consumption.
A brief review of recent literature on the prevalence of recreational cannabis use, the potency of modern cannabis preparations and the pharmacological actions of cannabis.
Cannabinoids derived from herbal cannabis interact with endogenous cannabinoid systems in the body. Actions on specific brain receptors cause dose-related impairments of psychomotor performance with implications for car and train driving, aeroplane piloting and academic performance. Other constituents of cannabis smoke carry respiratory and cardiovascular health risks similar to those of tobacco smoke.
Cannabis is not, as widely perceived, a harmless drug but poses risks to the individual and to society.
年轻人中消遣性使用大麻的现象日益普遍，引发了关于急性和长期使用大麻可能产生的影响的讨论。
强调近期关于大麻作用机制、对心理运动和认知表现的影响以及与大麻消费相关的健康风险的知识。
简要回顾近期关于消遣性使用大麻的流行情况、现代大麻制剂的效力以及大麻药理作用的文献。
来自草药大麻的大麻素与体内内源性大麻素系统相互作用。对特定脑受体的作用会导致与剂量相关的心理运动表现受损，这对汽车和火车驾驶、飞机驾驶以及学业成绩都有影响。大麻烟雾的其他成分带来的呼吸和心血管健康风险与烟草烟雾类似。
大麻并非如人们普遍认为的那样是一种无害药物，而是对个人和社会都构成风险。
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