Theerthakarai R, El-Halees W, Ismail M, Solis R A, Khan M A
Pulmonary Division, St. Joseph's Hospital and Medical Center Patterson, NJ 07503, USA.
Chest. 2001 Jan;119(1):181-4. doi: 10.1378/chest.119.1.181.
To assess the value of the initial microbiological studies (MBS), consisting of sputum Gram's stains, sputum cultures, and blood cultures, in the etiologic diagnosis of community-acquired pneumonia (CAP) without comorbidity.
A prospective study of 74 adult patients hospitalized with nonsevere CAP empirically treated according to the American Thoracic Society guidelines (ATS-GL) and evaluated with Gram's stains and cultures of valid sputum specimens and blood cultures.
University-affiliated community hospital.
Gram's stain of a valid sputum specimen failed to identify the etiologic agent in all patients. Sputum cultures identified pathogens in only four patients (5%). The results of all blood cultures were negative. All patients responded to the initial empiric antibiotic coverage selected according to the ATS-GL, and the results of the initial MBS had no clinical impact.
The initial MBS, such as sputum Gram's stains, sputum cultures, and blood cultures, have no value in the management of nonsevere CAP without comorbid factors.
评估由痰革兰氏染色、痰培养和血培养组成的初始微生物学检查（MBS）在无合并症的社区获得性肺炎（CAP）病因诊断中的价值。
一项对74例因非重症CAP住院的成年患者进行的前瞻性研究，这些患者根据美国胸科学会指南（ATS-GL）接受经验性治疗，并对有效的痰标本进行革兰氏染色和培养以及血培养。
大学附属医院。
所有患者的有效痰标本革兰氏染色均未鉴定出病原体。痰培养仅在4例患者（5%）中鉴定出病原体。所有血培养结果均为阴性。所有患者对根据ATS-GL选择的初始经验性抗生素覆盖治疗有反应，初始MBS结果无临床影响。
初始MBS，如痰革兰氏染色、痰培养和血培养，在无合并症因素的非重症CAP管理中无价值。
