库普弗细胞的膜结构对血液凝固的影响。
Effect of membranous structures of the Kupffer cells on blood clotting.
作者信息
Davydov V S, Mayanskaya N N, Viadimirova L F, Ganeeva R R
出版信息
Bull Exp Biol Med. 1975 Jan;77(7):726-8. doi: 10.1007/BF00799301.
PMID:1115847
Abstract
The effect of subcellular fractions of the endothelia kupffer cells on blood clotting was studied. Cells were obtained from the rabbit liver by magnetic fractionation and the subcellular structures were than isolated from them by differential centrifugation. The inner membranous structures were found to carry thromboplastic activity. No correlation was found between the blood-clotting potential of the intracellular structures of the endothelial cells and the level of their cathepsin C activity.
摘要
研究了肝巨噬细胞亚细胞组分对血液凝固的影响。通过磁性分离从兔肝脏获取细胞，然后通过差速离心从这些细胞中分离亚细胞结构。发现内部膜结构具有促凝血活性。在内皮细胞的细胞内结构的凝血潜能与其组织蛋白酶C活性水平之间未发现相关性。
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