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迟发型超敏反应在心肌过敏性病变发展过程中表现出来。

Hypersensitivity of delayed type manifested during the development of allergic lesions of the myocardium.

作者信息

Kalikshtein D B, Odinokova V A, Paleev N R, Gurevich M A

出版信息

Bull Exp Biol Med. 1975 Jan;77(7):789-91. doi: 10.1007/BF00799321.

DOI:10.1007/BF00799321
PMID:1115862
Abstract

Changes in humoral and cellular responses were studied during the development of allergic lesions of the myocardium in rabbits. These responses,manifestations of hypersensitivity of delayed type, are connected with transformation of cells of the active mesenchyme, responsible for the process of immuogenesis, into lymhocytes and plasma cells. In allergic lesions of the myocardium hypersensitivity of delayed type is manifested as lympho-marcrophagal reaction in the intermuscular stroma of the heart, the thymus, and lymph glands and also as blast transformation of the lymphocytes. A complex series of disturbances of immunologic homeostasis arises, in which the primary components are micronaglopahies, blast-transformation of the lymphoctes and activation of iysosomal enzymes.

摘要

在兔心肌过敏性病变发展过程中,对体液和细胞反应的变化进行了研究。这些反应是迟发型超敏反应的表现,与负责免疫发生过程的活性间充质细胞转化为淋巴细胞和浆细胞有关。在心肌过敏性病变中,迟发型超敏反应表现为心脏肌间基质、胸腺和淋巴结中的淋巴细胞 - 巨噬细胞反应,以及淋巴细胞的母细胞转化。出现了一系列复杂的免疫稳态紊乱,其中主要成分是微纳格洛菲(micronaglopahies,可能有误,原文可能表述有误)、淋巴细胞的母细胞转化和溶酶体酶的激活。

相似文献

1
Hypersensitivity of delayed type manifested during the development of allergic lesions of the myocardium.迟发型超敏反应在心肌过敏性病变发展过程中表现出来。
Bull Exp Biol Med. 1975 Jan;77(7):789-91. doi: 10.1007/BF00799321.
2
[Manifestations of delayed hypersensitivity in the development of an allergic lesion of the myocardium].[心肌过敏性病变发展过程中迟发型超敏反应的表现]
Biull Eksp Biol Med. 1974 Jul;78(7):73-6.
3
Skin reaction and blast transformation of lymphocytes of guinea pigs sensitized with trypsin inhibitors.用胰蛋白酶抑制剂致敏的豚鼠的皮肤反应和淋巴细胞的母细胞转化
Jpn J Exp Med. 1974 Dec;44(6):503-18.
4
[Kinin system of blood plasma in experimental allergic myocarditis].[实验性变应性心肌炎中血浆的激肽系统]
Kardiologiia. 1973 Feb;13(2):119-23.
5
[Allergic vasculitis in infectious-allergic myocarditis].[感染性变应性心肌炎中的变应性血管炎]
Sov Med. 1990(2):3-6.
6
[Delayed hypersensitivity indices in dogs with an excessive protein content in the diet].[饮食中蛋白质含量过高的犬类的迟发型超敏反应指标]
Vopr Pitan. 1978 May-Jun(3):27-9.
7
[Myocardial damage syndrome in allergic conditions].[过敏性疾病中的心肌损伤综合征]
Kardiologiia. 1975 Nov;15(11):27-30.
8
Specificity of blast transformation. I. Studies with organ- and species-specific antigens.母细胞转化的特异性。I. 针对器官特异性和物种特异性抗原的研究。
Int Arch Allergy Appl Immunol. 1970;39(5-6):479-87.
9
Increased cellular immunity against host cell antigens induced by vacciniavirus.牛痘病毒诱导的针对宿主细胞抗原的细胞免疫增强。
Arch Gesamte Virusforsch. 1974;45(1-2):122-7. doi: 10.1007/BF01240549.
10
Cellular and humoral immune responses in guinea pigs and rabbits to chemically defined synthetic peptides.豚鼠和兔子对化学合成特定肽的细胞免疫和体液免疫反应。
Eur J Immunol. 1973 Sep;3(9):574-9. doi: 10.1002/eji.1830030910.

本文引用的文献

1
A study of fixation for electron microscopy.电子显微镜固定研究。
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2
Acetone fixation for the cytochemical demonstration of dehydrogenases in blood and bone marrow cells.用于血液和骨髓细胞中脱氢酶细胞化学显示的丙酮固定法。
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3
The use of lead citrate at high pH as an electron-opaque stain in electron microscopy.在电子显微镜检查中,将高pH值的柠檬酸铅用作电子不透明染色剂。
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Hashimoto's thyroiditis. Ultrastructure and histochemistry of the cellular infiltrate.桥本甲状腺炎。细胞浸润的超微结构与组织化学
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[Modelling autoimmune processes and certain aspects of the pathogenesis of systemic lupus erythematosus].[系统性红斑狼疮自身免疫过程及发病机制某些方面的建模]
Sov Med. 1969 Sep;32(9):5-11.
6
[Delayed-type hypersensitivity].[迟发型超敏反应]
Arkh Patol. 1973;35(6):3-19.
7
[Debatable questions concerning our understanding of inflammation].关于我们对炎症理解的争议性问题
Arkh Patol. 1972;34(10):73-8.
8
[Morphologic changes in the myocardium following allergic damage].[变应性损伤后心肌的形态学变化]
Biull Eksp Biol Med. 1973 Mar;75(3):108-11.