Schlebusch H, Schander K, Sorger M, Harnack H
Fortschr Med. 1976 Nov 18;94(33):1895-9.
In order to evaluate liver function during pregnancy the enzyme activities of GPT, GOT, GLDH, LDH, AP, LAP, gamma-GT and CHE were determined in 272 healthy pregnant women from the 16th week of gestation up to term. The normal range of GPT, GOT, GLDH, LDH, gamma-GT and CHE did not differ significantly from those in non-pregnant women. Increases in AP and LAP are conditioned by placental synthesis. The functional reserves of a healthy liver obviously suffice to compensate for increased demands during pregnancy. Increases in enzyme aktivities during pregnancy are not physiologic - except for increases in AP and LAP.
为评估孕期肝功能,对272名从妊娠第16周直至足月的健康孕妇测定了谷丙转氨酶(GPT)、谷草转氨酶(GOT)、谷氨酸脱氢酶(GLDH)、乳酸脱氢酶(LDH)、碱性磷酸酶(AP)、亮氨酸氨基肽酶(LAP)、γ-谷氨酰转肽酶(γ-GT)和胆碱酯酶(CHE)的酶活性。GPT、GOT、GLDH、LDH、γ-GT和CHE的正常范围与非孕妇并无显著差异。AP和LAP的升高是由胎盘合成所致。健康肝脏的功能储备显然足以补偿孕期增加的需求。孕期酶活性的升高并非生理性的——AP和LAP升高除外。