[麻醉对肝脏酶及蛋白质组分术后行为的影响]
[The effect of anesthesia on the postoperative behavior of liver enzymes and protein fractions].
作者信息
Schlebusch H, Garstka G, Harnack H
出版信息
Fortschr Med. 1977 Mar 10;95(10):662-8.
Liver tests were performed postoperatively on 25 women with "healthy" livers. Patients were divided into 3 groups according to the type of anesthesia used: 1. halothane; 2. neuroleptic; 3. peridural. In all 3 groups the variations in serum proteins and liver enzymes were similar up to the 15th postoperative day. Variations of LDH, AP, LAP, and CHE were within normal range; slight to moderate increases above normal were observed for GPT, GOT, GLDH, and gamma-GT. All 3 groups barely differ with respect to enzyme levels during the postoperative course. We therefore interpret these changes to indicate a reaction of the liver to the stress of operation rather than to the mode of anesthesia.
对25名肝脏“健康”的女性患者在术后进行了肝功能检查。根据所使用的麻醉类型，将患者分为3组：1. 氟烷；2. 神经安定药；3. 硬膜外麻醉。在术后第15天之前，所有3组患者的血清蛋白和肝酶变化相似。乳酸脱氢酶（LDH）、碱性磷酸酶（AP）、亮氨酸氨基肽酶（LAP）和胆碱酯酶（CHE）的变化均在正常范围内；谷丙转氨酶（GPT）、谷草转氨酶（GOT）、谷氨酸脱氢酶（GLDH）和γ-谷氨酰转肽酶（gamma-GT）则有轻度至中度高于正常水平的情况。在术后过程中，所有3组的酶水平几乎没有差异。因此，我们认为这些变化表明肝脏是对手术应激而非麻醉方式产生的反应。
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