Versieck J, Barbier F, Speecke A, Hoste J
Clin Chem. 1975 Apr;21(4):578-81.
Reportedly, serum manganese concentrations increase after myocardial infarction, closely correlated with increased serum aspartate aminotransferase activity. However, these conclusions are apparently based on analyses of contaminated samples. Serum manganese concentrations after myocardial infarction have been re-investigated by neutron activation analysis, and no significant increase could be demonstrated. Because serum copper and zinc could be determined simultaneously, analyses for these trace elements are also reported, which confirm the findings of others. After myocardial infarction a statistically significant (0.02 smaller than P smaller than 0.05) increase in serum copper and a statistically significant (0.001 smaller than P smaller than 0.01) decrease in serum zinc were observed.
据报道，心肌梗死后血清锰浓度会升高，与血清天冬氨酸氨基转移酶活性增加密切相关。然而，这些结论显然是基于对受污染样本的分析。通过中子活化分析对心肌梗死后的血清锰浓度进行了重新研究，未发现有显著升高。由于血清铜和锌可以同时测定，因此也报告了对这些微量元素的分析结果，这些结果证实了其他研究人员的发现。心肌梗死后，观察到血清铜有统计学意义的升高（0.02＜P＜0.05），血清锌有统计学意义的降低（0.001＜P＜0.01）。
