Selective permeabilization of infected host cells with pore-forming proteins provides a novel tool to study protein synthesis and viability of the intracellular apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii.
作者信息
Baumeister S, Paprotka K, Bhakdi S, Lingelbach K
机构信息
FB Biologie/Zoologie, Philipps Universität Marburg, 35032 Marburg, Germany.
出版信息
Mol Biochem Parasitol. 2001 Jan 15;112(1):133-7. doi: 10.1016/s0166-6851(00)00343-1.
Abstract
摘要
相似文献
1
Selective permeabilization of infected host cells with pore-forming proteins provides a novel tool to study protein synthesis and viability of the intracellular apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii.用成孔蛋白对受感染的宿主细胞进行选择性通透化处理，为研究细胞内顶复门寄生虫恶性疟原虫和刚地弓形虫的蛋白质合成及生存能力提供了一种新工具。
Mol Biochem Parasitol. 2001 Jan 15;112(1):133-7. doi: 10.1016/s0166-6851(00)00343-1.
2
Permeabilization of the erythrocyte membrane with streptolysin O allows access to the vacuolar membrane of Plasmodium falciparum and a molecular analysis of membrane topology.用链球菌溶血素O使红细胞膜通透，可接触到恶性疟原虫的液泡膜并对膜拓扑结构进行分子分析。
Mol Biochem Parasitol. 1997 Feb;84(2):259-61. doi: 10.1016/s0166-6851(96)02806-x.
3
Comparative analysis of stage specific gene regulation of apicomplexan parasites: Plasmodium falciparum and Toxoplasma gondii.疟原虫和弓形虫等顶复门寄生虫阶段特异性基因调控的比较分析
Infect Disord Drug Targets. 2010 Aug;10(4):240-1. doi: 10.2174/187152610791591584.
4
Characterization of Plasmodium Atg3-Atg8 Interaction Inhibitors Identifies Novel Alternative Mechanisms of Action in Toxoplasma gondii.鉴定疟原虫 Atg3-Atg8 相互作用抑制剂的特性，确定刚地弓形虫中的新型作用机制。
Antimicrob Agents Chemother. 2018 Jan 25;62(2). doi: 10.1128/AAC.01489-17. Print 2018 Feb.
5
Protein sorting in Plasmodium falciparum-infected red blood cells permeabilized with the pore-forming protein streptolysin O.用成孔蛋白链球菌溶血素O使恶性疟原虫感染的红细胞通透后进行蛋白质分选。
Biochem J. 1996 Apr 1;315 ( Pt 1)(Pt 1):307-14. doi: 10.1042/bj3150307.
6
Supply and demand-heme synthesis, salvage and utilization by Apicomplexa.供应与需求-疟原虫的血红素合成、回收与利用。
FEBS J. 2021 Jan;288(2):382-404. doi: 10.1111/febs.15445. Epub 2020 Jun 23.
7
Apicomplexan actin polymerization depends on nucleation.质体锥虫肌动蛋白聚合依赖于成核。
Sci Rep. 2017 Sep 22;7(1):12137. doi: 10.1038/s41598-017-11330-w.
8
Apicomplexan parasites co-opt host calpains to facilitate their escape from infected cells.顶复门寄生虫利用宿主的钙蛋白酶来促进它们从被感染的细胞中逃脱。
Science. 2009 May 8;324(5928):794-7. doi: 10.1126/science.1171085. Epub 2009 Apr 2.
9
Protein targeting from malaria parasites to host erythrocytes.疟原虫蛋白质向宿主红细胞的靶向运输。
Traffic. 2005 Aug;6(8):706-9. doi: 10.1111/j.1600-0854.2005.00310.x.
10
Ribosomal protein P2 localizes to the parasite zoite-surface and is a target for invasion inhibitory antibodies in Toxoplasma gondii and Plasmodium falciparum.核糖体蛋白P2定位于寄生虫动合子表面，是刚地弓形虫和恶性疟原虫中入侵抑制抗体的作用靶点。
Parasitol Int. 2015 Feb;64(1):43-9. doi: 10.1016/j.parint.2014.08.006. Epub 2014 Sep 30.
引用本文的文献
1
Selective permeabilization of the host cell membrane of Plasmodium falciparum-infected red blood cells with streptolysin O and equinatoxin II.用链球菌溶血素O和海葵毒素II对恶性疟原虫感染的红细胞的宿主细胞膜进行选择性通透化处理。
Biochem J. 2007 Apr 1;403(1):167-75. doi: 10.1042/BJ20061725.
2
Delivery of the malaria virulence protein PfEMP1 to the erythrocyte surface requires cholesterol-rich domains.将疟疾毒力蛋白PfEMP1递送至红细胞表面需要富含胆固醇的结构域。
Eukaryot Cell. 2006 May;5(5):849-60. doi: 10.1128/EC.5.5.849-860.2006.
3
Correct promoter control is needed for trafficking of the ring-infected erythrocyte surface antigen to the host cytosol in transfected malaria parasites.在转染的疟原虫中，将环感染红细胞表面抗原转运至宿主细胞质需要正确的启动子控制。
Infect Immun. 2004 Oct;72(10):6095-105. doi: 10.1128/IAI.72.10.6095-6105.2004.
Zotero 插件