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微管与膜结合小泡之间存在紧密联系的证据。

Evidence for firm linkages between microtubules and membrane-bounded vesicles.

作者信息

Allen R D

出版信息

J Cell Biol. 1975 Feb;64(2):497-503. doi: 10.1083/jcb.64.2.497.

Abstract

Direct evidence is presented in support of the widely held idea that membrane-bounded vesicles can bind firmly to microtubules. This is shown in P. caudatum which contains ribbons of straight microtubules located in open cytoplasm and uniquely associated with the disk-shaped vesicles. These vesicles frequently lie flat against the face of the ribbons at a constant distance of 30-40 nm. Under certain conditions the ribbons are compressed into zigzag pattern, but the vesicles continue to maintain their 30-40 nm spacing with the tubules and The author's interpretation of this phenomena is that the vesicles and the microtubules are strongly bound together. This interaction appears to be via a filamentous material rather than bridges.

摘要

有直接证据支持广泛认可的观点,即膜结合囊泡可牢固地附着于微管。这在尾草履虫中得到了证明,其含有位于开放细胞质中的直微管带,且这些微管带与盘状囊泡独特相关。这些囊泡常常以30 - 40纳米的恒定距离平贴在微管带表面。在某些条件下,微管带会被压缩成锯齿状图案,但囊泡仍继续与微管保持30 - 40纳米的间距。作者对这种现象的解释是,囊泡和微管紧密结合在一起。这种相互作用似乎是通过丝状物质而非桥接结构实现的。

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