从西印度海鞭华丽拟软珊瑚（Pseudopterogorgia elisabethae）中分离出的具有抗分枝杆菌活性的锯齿烷二萜类化合物。
Serrulatane diterpenes with antimycobacterial activity isolated from the West Indian sea whip Pseudopterogorgia elisabethae.
作者信息
Rodríguez A D, Ramírez C
机构信息
Department of Chemistry, University of Puerto Rico, P.O. Box 23346, San Juan, Puerto Rico 00931-3346, USA.
出版信息
J Nat Prod. 2001 Jan;64(1):100-2. doi: 10.1021/np000196g.
PMID:11170678
Abstract
Two new antimycobacterial serrulatane diterpenes, erogorgiaene (3) and 7-hydroxyerogorgiaene (4), and a novel C(40) bisditerpene (5), have been isolated from the West Indian gorgonian octocoral Pseudopterogorgia elisabethae. The structures of compounds 3-5 were determined by spectral (1D and 2D NMR, IR, UV, and HREIMS) analysis.
摘要
从西印度柳珊瑚八放珊瑚伊丽莎白拟软柳珊瑚（Pseudopterogorgia elisabethae）中分离出了两种新的抗分枝杆菌锯齿烷二萜类化合物，即异软柳珊瑚烯（3）和7-羟基异软柳珊瑚烯（4），以及一种新型的C(40)双二萜（5）。通过光谱分析（一维和二维核磁共振、红外、紫外和高分辨电子轰击质谱）确定了化合物3至5的结构。
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