Sequential blood samples from the tail vein of rats and mice obtained with modified Liebig condenser jackets and vacuum.

A simple method for obtaining multiple, sizeable blood samples rapidly and sequentially from mice and rats without the use of anesthesia utilizing an adapted Liebig condenser jacket connected to a vacuum line is described. The method permits the removal and insertion of sample tubes during the procedure so that anticoagulated and clotted specimens can be obtained during a single bleeding.