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短暂性卵巢功能衰竭:子宫动脉栓塞术的一种并发症。

Transient ovarian failure: a complication of uterine artery embolization.

作者信息

Amato P, Roberts A C

机构信息

Department of Reproductive Medicine, University of California, La Jolla, California, USA.

出版信息

Fertil Steril. 2001 Feb;75(2):438-9. doi: 10.1016/s0015-0282(00)01678-2.

Abstract

OBJECTIVE

To report a case of transient ovarian failure shortly after arterial embolization for treatment of uterine fibroids, followed by recovery of ovarian function.

DESIGN

Case report.

SETTING

A university-based hospital.

PATIENT

A 49-year-old woman with menorrhagia and anemia secondary to uterine fibroids and refractory to medical management. The follicle-stimulating hormone (FSH) level on cycle day 3 before the procedure was 8.2 mIU/mL.

INTERVENTION(S): Bilateral uterine artery embolization for treatment of menorrhagia.

MAIN OUTCOME MEASURE(S): Serum FSH level.

RESULT(S): The patient developed amenorrhea and hot flashes 3 months after uterine artery embolization. Her serum FSH level at that time was 140.1 mIU/mL. Four months later, uterine bleeding resumed; her serum FSH level was 2.1 mIU/mL.

CONCLUSION(S): Uterine artery embolization may hasten ovarian failure. This procedure should be reserved for women who have completed their child-bearing or are poor candidates for myomectomy. Patients should be counseled appropriately about the risk of possible ovarian failure.

摘要

目的

报告一例子宫肌瘤动脉栓塞治疗后短期内出现短暂性卵巢功能衰竭,随后卵巢功能恢复的病例。

设计

病例报告。

单位

一所大学附属医院。

患者

一名49岁女性,因子宫肌瘤导致月经过多和贫血,药物治疗无效。术前第3天周期的促卵泡生成素(FSH)水平为8.2 mIU/mL。

干预措施

双侧子宫动脉栓塞治疗月经过多。

主要观察指标

血清FSH水平。

结果

子宫动脉栓塞术后3个月,患者出现闭经和潮热。当时她的血清FSH水平为140.1 mIU/mL。4个月后,子宫出血恢复;她的血清FSH水平为2.1 mIU/mL。

结论

子宫动脉栓塞可能加速卵巢功能衰竭。该手术应仅用于已完成生育或不适合行肌瘤切除术的女性。应向患者充分告知可能出现卵巢功能衰竭的风险。

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