Dorchy H
Diabetology Clinic, University Children's Hospital Queen Fabiola, Avenue J.J. Crocq, 15, B1020 Bruxelles, Belgium.
Diabetes Metab. 2000 Dec;26(6):500-7.
Because recent multicenter studies, even those performed in developed countries without financial restriction, show that treatment of childhood diabetes is inadequate in general and that levels of glycated hemoglobin (HbA1c) are very different, diabetes treatment teams should individually explore the reasons for failure, without any prejudice or bias. The "good" treatment is signed by good HbA1c associated with good quality of life, and is not necessarily exportable without adjustment to the local way of life. HbA1c must be under 7%, if the upper normal limit is about 6%, which is possible, in our experience, even in diabetic children and adolescents. Our "recipes" are summarized. The number of daily insulin injections, 2 or 4, by itself does not necessarily give better results, but the 4-injection regimen allows greater freedom, taking into account that the proper insulin adjustment is difficult before adolescence. Successful glycemic control in young patients depends mainly on the quality and intensity of diabetes education. Any dogmatism must be avoided; only the objective result is important.
因为最近的多中心研究表明,即使是在没有资金限制的发达国家开展的研究,总体上儿童糖尿病的治疗也并不充分,糖化血红蛋白(HbA1c)水平差异很大,所以糖尿病治疗团队应各自探寻治疗失败的原因,不带任何成见或偏见。“良好”的治疗表现为HbA1c良好且生活质量良好,而且未经根据当地生活方式调整就不一定能照搬。如果正常上限约为6%,HbA1c必须低于7%,根据我们的经验,即使在糖尿病儿童和青少年中这也是有可能实现的。我们总结了“秘诀”。每日胰岛素注射次数为2次或4次,其本身不一定能带来更好的效果,但4次注射方案能提供更大的灵活性,因为考虑到在青春期前进行适当的胰岛素调整很困难。年轻患者血糖的成功控制主要取决于糖尿病教育的质量和强度。必须避免任何教条主义;只有客观结果才重要。