Constable A R, Hussein M M, Albrecht M P, Thompson F D, Philalithis P E, Joekes A M
Br J Urol. 1979 Apr;51(2):84-7. doi: 10.1111/j.1464-410x.1979.tb02837.x.
Thirty adult patients were investigated with 36 125I Hippuran and 40 51Cr EDTA single injection clearance studies. "Volumes of distribution" obtained from single samples have been correlated with the slope clearances and regression equations have been determined. From these equations it is possible to determine glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) from single plasma samples and the method is sufficiently accurate for routine application.
对30名成年患者进行了研究,采用36次125I马尿酸盐和40次51Cr依地酸盐单次注射清除率研究。从单次样本获得的“分布容积”已与斜率清除率相关联,并确定了回归方程。根据这些方程,可以从单次血浆样本中确定肾小球滤过率(GFR)和有效肾血浆流量(ERPF),该方法对于常规应用来说足够准确。