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通过放射自显影术研究剑尾鱼(Xiphophorus maculatus)前脑中雌激素靶细胞的拓扑分布。

Topographical distribution of estrogen target cells in the forebrain of platyfish, Xiphophorus maculatus, studied by autoradiography.

作者信息

Kim Y S, Stumpf W E, Sar M

出版信息

Brain Res. 1979 Jul 6;170(1):43-59. doi: 10.1016/0006-8993(79)90939-9.

DOI:10.1016/0006-8993(79)90939-9
PMID:111768
Abstract

In the platyfish, Xiphophorus maculatus, after injection of [3H]estradiol-17 beta, nuclear concentration of radioactivity is observed in certain cells of the forebrain. These labeled cells are accumulated in periventricular midline regions that include in the telencephalon the ventral precommissural and dorsal supracommissural areas, and in the diencephalon the preoptic, central hypothalamic and thalamic areas. The specialized ependyma of the subcommissural organ also shows nuclear concentration of radioactivity, while other ependymal cells remain unlabeled. Similar to other vertebrate classes, the accumulations of estrogen target cells exist characteristically in the vicinity of the ventricular system, especially its recesses. This implies close topographical relationships between estrogen target cells and the ventricular recess organs, including the optic recess organ, the infundibular recess organ, the paraventricular organ and the subcommissural organ. Different from other vertebrate classes, no pallial accumulations of estrogen target cells are seen in the teleost.

摘要

在剑尾鱼(Xiphophorus maculatus)中,注射[3H]雌二醇-17β后,在前脑的某些细胞中观察到放射性物质的核内聚集。这些标记细胞聚集在脑室周围的中线区域,在端脑中包括腹侧连合前区和背侧连合上区,在间脑中包括视前区、下丘脑中央区和丘脑区。连合下器官的特化室管膜也显示出放射性物质的核内聚集,而其他室管膜细胞未被标记。与其他脊椎动物类群相似,雌激素靶细胞的聚集特征性地存在于脑室系统附近,尤其是其隐窝处。这意味着雌激素靶细胞与脑室隐窝器官之间存在密切的拓扑关系,包括视隐窝器官、漏斗隐窝器官、室旁器官和连合下器官。与其他脊椎动物类群不同的是,硬骨鱼中未观察到雌激素靶细胞在大脑皮质的聚集。

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