Tamai K, Mitsumori M, Fujishiro S, Kokubo M, Ooya N, Nagata Y, Sasai K, Hiraoka M, Inamoto T
Department of Therapeutic Radiology and Oncology, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.
Breast Cancer. 2001;8(1):90-2. doi: 10.1007/BF02967485.
We report a case of a 28-year-old woman with right-sided breast cancer. The patient had been treated for atopic dermatitis since her infancy. She underwent breast-conserving surgery (BCS) in July 1998, and three titanium clips were placed at the margin of the excision cavity at the time of surgery. Two months after surgery, the patient exhibited a rapid exacerbation of atopic dermatitis. Various drugs were suspected to be the cause of the allergic reaction, but the results of a bi-digital O-ring test (BDORT) suggested an allergic reaction to titanium clips. In August 1999, the patient underwent a second operation to remove the titanium clips under local anesthesia. Allergy to surgical titanium clips is a rare complication, but in patients with a history of severe allergic diseases, a preoperative immunologic examination should be performed and the patient's history of metal allergy should be investigated.
我们报告一例28岁的右侧乳腺癌女性患者。该患者自婴儿期起就患有特应性皮炎。1998年7月她接受了保乳手术（BCS），手术时在切除腔边缘放置了三个钛夹。术后两个月，患者特应性皮炎迅速加重。怀疑多种药物是过敏反应的原因，但双指O形环试验（BDORT）结果提示对钛夹过敏。1999年8月，患者在局部麻醉下接受了第二次手术以取出钛夹。手术钛夹过敏是一种罕见的并发症，但对于有严重过敏疾病史的患者，应进行术前免疫学检查并调查患者的金属过敏史。
