Davis R H, Sackman J W, Kramer D L, Balin H
Obstet Gynecol. 1975 Feb;45(2):190-2.
In this study C3H/HeJ female mice received an intraperitoneal injection of mammary tumor suspended in saline; After 14 days, the presence of mammary neoplasm was detected by a significant change in the cytodifferential counts of aspirated peritoneal fluid. Previous studies suggest that ovarian cancer can be detected in mice and in women by the characteristic changes produced in abdominal cellular fluid distribution.
在本研究中,C3H/HeJ雌性小鼠接受了腹腔注射用生理盐水悬浮的乳腺肿瘤;14天后,通过吸出的腹腔液细胞分化计数的显著变化检测到乳腺肿瘤的存在。先前的研究表明,通过腹部细胞液分布产生的特征性变化,可以在小鼠和女性中检测到卵巢癌。