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大鼠大脑皮质微循环床中的肌源性紧张和神经源性血管收缩

Myogenic tone and neurogenic vasoconstriction in microcirculatory bed of rat cerebral cortex.

作者信息

Timkina M I

机构信息

Laboratory of General Pathology Microcirculation, Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia.

出版信息

Bull Exp Biol Med. 2000 Nov;130(11):1045-7.

Abstract

The reaction of rat parietal cortical vessels to stimulation of the sympathetic ganglion was studied by intravital microscopy. stimulation induced constriction of cerebral arterioles. Clamping of one or both carotid arteries led to myogenic vasodilatation in the majority of cases. Constrictive response of brain arterioles to ganglion stimulation under conditions carotid occlusion did not differ from that under conditions of baseline cerebral blood supply.

摘要

通过活体显微镜研究了大鼠顶叶皮质血管对交感神经节刺激的反应。刺激可引起脑小动脉收缩。在大多数情况下,夹闭一侧或双侧颈动脉会导致肌源性血管舒张。在颈动脉闭塞的情况下,脑小动脉对神经节刺激的收缩反应与脑血流供应基线条件下的反应没有差异。

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