Chernukh A M, Krzhechek I, Zikha I, Timkin M I
Biull Eksp Biol Med. 1981 Dec;92(12):645-8.
Acute experiments on anesthetized rats were made to study the time course of cardiac output (Cardiogreen dilution method) and systemic arterial pressure during electrical stimulation of the celiac ganglion. In other series of experiments a study was made of the time course of microcirculatory changes in the mesentery under the same conditions and with the use of intravital microscopy. An appreciable increase in the minute volume (23.44 +/- 4.91) was revealed 6 s after the onset of the stimulation. The increase in arterial pressure amounted to 7.06 +/- 2.45%. The increase of arterial pressure in the second series of experiments was 18.8 +/- 2.2%, and vasoconstriction 4.1 +/- 1.6% (the initial diameter of the vessels being 264.59 +/- 4.50 micrometers). Celiac ganglion stimulation led to a progressive deceleration of the blood flow and stoppage of the blood flow, with the diameter of the microvessels remaining unchanged. Regression analysis of the data obtained allows the conclusion that microcirculatory changes seen in the mesentery and initial hypertensive response are consequent on the increased cardiac output, on the one hand, and on the constriction of the mesenterial vessels, on the other.
对麻醉大鼠进行急性实验，以研究在电刺激腹腔神经节期间心输出量（心绿素稀释法）和体循环动脉压的时程。在其他系列实验中，在相同条件下并使用活体显微镜研究了肠系膜微循环变化的时程。刺激开始6秒后，发现每分输出量有明显增加（23.44±4.91）。动脉压升高达7.06±2.45%。在第二系列实验中，动脉压升高为18.8±2.2%，血管收缩为4.1±1.6%（血管初始直径为264.59±4.50微米）。刺激腹腔神经节导致血流逐渐减慢并停止，微血管直径保持不变。对所得数据的回归分析得出结论：一方面，肠系膜中所见的微循环变化和初始高血压反应是心输出量增加的结果；另一方面，是肠系膜血管收缩的结果。
