Hughes C M, Lapane K L, Mor V
School of Pharmacy, The Queen's University of Belfast, Northern Ireland.
Med Care. 2000 Dec;38(12):1164-73. doi: 10.1097/00005650-200012000-00003.
This study investigated the effect of facility and resident characteristics on the use of antipsychotic medications in the long-term care setting.
This research used data available from the On-Line Survey and Certification of Automated Records (OSCAR) for all Medicare/Medicaid-certified nursing homes in the contiguous United States in 1997. The data consisted of 14,631 facilities.
A multiple linear regression model was used to determine the effects of selected facility and resident characteristics on antipsychotic drug use while simultaneously controlling for the effects of resident characteristics and stratifying by ownership type. beta-Coefficients provided measures of effect and represented the per-unit change in the prevalence of antipsychotic use corresponding to the per-unit change in each independent variable.
In for-profit facilities, both the presence of special care units and mental health professionals were associated with increased antipsychotic use (beta = 1.70, SE = 0.23; beta = 0.24, SE = 0.17, respectively), while other facility factors such as increasing size, being part of a chain, and higher occupancy rate were associated with decreased antipsychotic drug use. In the nonprofit environment, facility characteristics (eg, increasing occupancy rate, certified nurses' aides per 100 beds) were associated with decreasing antipsychotic use. Increasing percentages of residents covered by Medicare, those with dementia, and residents with mental retardation (beta = 0.05, SE = 0.01; beta = 0.03, SE = 0.01; beta = 0.08, SE = 0.08, respectively) were predictive of increased drug use.
Facility and resident characteristics are associated with use of antipsychotic medications, although the extent to which these factors explain variability in use of anti-psychotics may vary on the basis of the underlying financial incentives of the institution.
本研究调查了机构特征和居民特征对长期护理机构中使用抗精神病药物的影响。
本研究使用了1997年美国本土所有医疗保险/医疗补助认证疗养院的在线调查与自动记录认证(OSCAR)中的可用数据。数据包含14631个机构。
采用多元线性回归模型来确定所选机构和居民特征对抗精神病药物使用的影响,同时控制居民特征的影响并按所有权类型进行分层。β系数提供了效应量度,代表抗精神病药物使用患病率每单位变化对应于每个自变量每单位变化的情况。
在营利性机构中,特殊护理单元的存在和心理健康专业人员都与抗精神病药物使用增加相关(β分别为1.70,标准误 = 0.23;β为0.24,标准误 = 0.17),而其他机构因素,如规模扩大、属于连锁机构以及入住率较高,则与抗精神病药物使用减少相关。在非营利环境中,机构特征(如入住率增加、每100张床位的注册护士助理人数)与抗精神病药物使用减少相关。医疗保险覆盖居民比例增加、患有痴呆症的居民以及患有智力障碍的居民(β分别为0.05,标准误 = 0.01;β为0.03,标准误 = 0.01;β为0.08,标准误 = 0.08)可预测药物使用增加。
机构和居民特征与抗精神病药物的使用相关,尽管这些因素在多大程度上解释了抗精神病药物使用差异可能因机构的潜在财务激励因素而异。