Department of Organizational Systems and Adult Health, University of Maryland School of Nursing, Baltimore, Maryland, USA.
Department of Epidemiology & Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Clin Gerontol. 2024 Oct-Dec;47(5):778-788. doi: 10.1080/07317115.2024.2346906. Epub 2024 May 19.
To describe nursing home (NH) characteristics associated with antipsychotic use and test whether associations changed after implementation of the National Partnership to Improve Dementia Care's antipsychotic reduction initiative (ARI).
Longitudinal quasi-experimental design using data from multiple sources and piecewise linear mixed models were used for statistical analyses.
There was a significant decrease in monthly antipsychotic use across the study period (pre-ARI b = -0.0003, p <.001; post-ARI b = -0.0012, p <.001), which held after adjusting for NH characteristics. Registered nurse hours (b = -0.0026, p <.001), licensed practical nurse hours (b = -0.0019, p <.001), facility chain membership (b = -0.0013, p <.01), and health inspection ratings (b = -0.0003, p >.01) were associated with decreased antipsychotic use. Post-ARI changes in associations between NH characteristics and antipsychotic use were small and not statistically significant.
Decreases in antipsychotic use were associated with most NH characteristics, and associations persisted post-ARI. Further research is warranted to examine the interactions between ARI policy and NH characteristics on antipsychotic prescribing, as well as other NH factors, such as facility prescribing cultures and clinical specialty of staff.
Decreases in monthly antipsychotic use were observed following the ARI. The decreases in monthly antipsychotic use were associated with most NH characteristics, and these associations persisted during the post-ARI period.
描述与抗精神病药物使用相关的养老院(NH)特征,并检验在实施国家改善痴呆症护理伙伴关系的抗精神病药物减少倡议(ARI)后,这些关联是否发生变化。
使用来自多个来源的数据和分段线性混合模型进行纵向准实验设计进行统计分析。
在研究期间,每月抗精神病药物的使用量呈显著下降趋势(ARI 前 b=-0.0003,p<.001;ARI 后 b=-0.0012,p<.001),调整 NH 特征后仍保持不变。注册护士小时数(b=-0.0026,p<.001)、持照实习护士小时数(b=-0.0019,p<.001)、机构连锁成员资格(b=-0.0013,p<.01)和健康检查评级(b=-0.0003,p>.01)与抗精神病药物使用减少有关。ARI 后,NH 特征与抗精神病药物使用之间的关联变化较小,且无统计学意义。
抗精神病药物使用的减少与大多数 NH 特征有关,并且在 ARI 后仍然存在。需要进一步研究,以检查 ARI 政策与 NH 特征对开处方行为的相互作用,以及其他 NH 因素,如机构开处方文化和工作人员的临床专业知识。
ARI 后观察到每月抗精神病药物使用量下降。每月抗精神病药物使用量的下降与大多数 NH 特征有关,并且这些关联在 ARI 后期间持续存在。