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初乳、唾液和羊水中的人免疫球蛋白D

Human immunoglobulin D in colostrum, saliva and amniotic fluid.

作者信息

Sewell H F, Matthews J B, Flack V, Jefferis R

出版信息

Clin Exp Immunol. 1979 Apr;36(1):183-8.

PMID:111882
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1537701/
Abstract

An antiserum raised to a partially purified preparation of secretory IgA isolated from human colostrum was shown to contain antibodies directed against human IgD. The inferred presence of IgD in the human colostrum was confirmed and also its association with antibody activity, as demonstrated by the presence of anti-E. coli antibodies. IgD was also shown to be present in whole saliva, parotid saliva and amniotic fluid, but could not be detected in jejunal juice.

摘要

一种针对从人初乳中分离出的部分纯化分泌型 IgA 制剂产生的抗血清，被证明含有针对人 IgD 的抗体。人初乳中 IgD 的推测存在得到了证实，其与抗体活性的关联也得到了证实，如抗大肠杆菌抗体的存在所证明。IgD 还被证明存在于全唾液、腮腺唾液和羊水中，但在空肠液中未检测到。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f97/1537701/39a4e9414d47/clinexpimmunol00205-0194-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f97/1537701/98acea6bf9e5/clinexpimmunol00205-0193-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f97/1537701/39a4e9414d47/clinexpimmunol00205-0194-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f97/1537701/98acea6bf9e5/clinexpimmunol00205-0193-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f97/1537701/39a4e9414d47/clinexpimmunol00205-0194-a.jpg

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Human immunoglobulin D in colostrum, saliva and amniotic fluid.初乳、唾液和羊水中的人免疫球蛋白D
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2
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本文引用的文献

1
CHARACTERISTICS OF AN IMMUNE SYSTEM COMMON TO CERTAIN EXTERNAL SECRETIONS.某些外分泌液共有的免疫系统特征。
J Exp Med. 1965 Jan 1;121(1):101-24. doi: 10.1084/jem.121.1.101.
2
GAMMA-GLOBULINS: QUANTITATIVE RELATIONSHIPS IN HUMAN SERUM AND NONVASCULAR FLUIDS.γ球蛋白：人血清和非血管性体液中的定量关系
Science. 1963 Nov 22;142(3595):1080-1. doi: 10.1126/science.142.3595.1080.
3
Comparative immunological studies of the immune globulins of human milk and of blood serum.人乳与血清免疫球蛋白的比较免疫学研究。
Int Arch Allergy Appl Immunol. 1961;18:241-67. doi: 10.1159/000229177.
4
Noval subunit in secretory IgA.分泌型免疫球蛋白A中的新亚基。
Nature. 1970 Dec 26;228(5278):1276-8. doi: 10.1038/2281276a0.
5
Protein uptake by the intestine: evidence for absorption of intact macromolecules.肠道对蛋白质的摄取：完整大分子吸收的证据。
Gastroenterology. 1974 May;66(5):987-92.
6
Immunoglobulin D in serum, body fluids and lymphoid tissues.血清、体液及淋巴组织中的免疫球蛋白D
Clin Exp Immunol. 1968 Jul;3(6):477-90.
7
Immunoglobulin levels in healthy children.健康儿童的免疫球蛋白水平。
Acta Paediatr Scand. 1967 Nov;56(6):572-9. doi: 10.1111/j.1651-2227.1967.tb15982.x.
8
Human secretory immunoglobulins. II. Salivary secretions from individuals with selectively excessive or defective synthesis of serum immunoglobulins.人类分泌型免疫球蛋白。II.血清免疫球蛋白合成选择性过度或缺陷个体的唾液分泌。
Clin Exp Immunol. 1971 Jan;8(1):69-85.
9
The chromic chloride method of coupling antigens to erythrocytes: definition of some important parameters.将抗原与红细胞偶联的氯化铬方法：一些重要参数的定义
J Immunol Methods. 1976;10(1):61-6. doi: 10.1016/0022-1759(76)90007-7.
10
Antibody production by human colostral cells. I. Immunoglobulin class, specificity, and quantity.人初乳细胞的抗体产生。I. 免疫球蛋白类别、特异性及数量。
Scand J Immunol. 1975 Sep;4(5-6):535-9. doi: 10.1111/j.1365-3083.1975.tb02659.x.