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高能光子束中圆柱形电离室的吸收剂量射束质转换因子。

Absorbed-dose beam quality conversion factors for cylindrical chambers in high energy photon beams.

作者信息

Seuntjens J P, Ross C K, Shortt K R, Rogers D W

机构信息

Ionizing Radiation Standards, Institute for National Measurement Standards, National Research Council of Canada, Ottawa.

出版信息

Med Phys. 2000 Dec;27(12):2763-79. doi: 10.1118/1.1328081.

Abstract

Recent working groups of the AAPM [Almond et al., Med. Phys. 26, 1847 (1999)] and the IAEA (Andreo et al., Draft V.7 of "An International Code of Practice for Dosimetry based on Standards of Absorbed Dose to Water," IAEA, 2000) have described guidelines to base reference dosimetry of high energy photon beams on absorbed dose to water standards. In these protocols use is made of the absorbed-dose beam quality conversion factor, kQ which scales an absorbed-dose calibration factor at the reference quality 60Co to a quality Q, and which is calculated based on state-of-the-art ion chamber theory and data. In this paper we present the measurement and analysis of beam quality conversion factors kQ for cylindrical chambers in high-energy photon beams. At least three chambers of six different types were calibrated against the Canadian primary standard for absorbed dose based on a sealed water calorimeter at 60Co [TPR10(20)=0.572, %dd(10)x=58.4], 10 MV [TPR10(20)=0.682, %dd(10)x=69.6), 20 MV (TPR10(20)=0.758, %dd(10)x= 80.5] and 30 MV [TPR10(20) = 0.794, %dd(10)x= 88.4]. The uncertainty on the calorimetric determination of kQ for a single chamber is typically 0.36% and the overall 1sigma uncertainty on a set of chambers of the same type is typically 0.45%. The maximum deviation between a measured kQ and the TG-51 protocol value is 0.8%. The overall rms deviation between measurement and the TG-51 values, based on 20 chambers at the three energies, is 0.41%. When the effect of a 1 mm PMMA waterproofing sleeve is taken into account in the calculations, the maximum deviation is 1.1% and the overall rms deviation between measurement and calculation 0.48%. When the beam is specified using TPR10(20), and measurements are compared with kQ values calculated using the version of TG-21 with corrected formalism and data, differences are up to 1.6% when no sleeve corrections are taken into account. For the NE2571 and the NE2611A chamber types, for which the most literature data are available, using %dd(10)x, all published data show a spread of 0.4% and 0.6%, respectively, over the entire measurement range, compared to spreads of up to 1.1% for both chambers when the kQ values are expressed as a function of TPR10(20). For the PR06-C chamber no clear preference of beam quality specifier could be identified. When comparing the differences of our kQ measurements and calculations with an analysis in terms of air-kerma protocols with the same underlying calculations but expressed in terms of a compound conversion factor CQ, we observe that a system making use of absorbed-dose calibrations and calculated kQ values, is more accurate than a system based on air-kerma calibrations in combination with calculated CQ (rms deviation of 0.48% versus 0.67%, respectively).

摘要

美国医学物理师协会(AAPM)的近期工作组[阿尔蒙德等人,《医学物理》26, 1847 (1999)]以及国际原子能机构(IAEA)(安德烈奥等人,《基于水吸收剂量标准的剂量测定国际操作规范》草案V.7,IAEA,2000)已经描述了基于水吸收剂量标准进行高能光子束参考剂量测定的指南。在这些协议中,使用了吸收剂量束质转换因子kQ,它将参考质60Co下的吸收剂量校准因子按比例换算到质Q,并且是根据最新的电离室理论和数据计算得出的。在本文中,我们给出了高能光子束中圆柱形电离室的束质转换因子kQ的测量与分析。至少对六种不同类型的三个电离室进行了校准,校准依据的是基于密封水热计在60Co [TPR10(20)=0.572,%dd(10)x=58.4]、10 MV [TPR10(20)=0.682,%dd(10)x=69.6]、20 MV [TPR10(20)=0.758,%dd(10)x=80.5]和30 MV [TPR10(20)=0.794,%dd(10)x=88.4]时的加拿大吸收剂量初级标准。单个电离室kQ的量热法测定的不确定度通常为0.36%,同一类型一组电离室的总体1σ不确定度通常为0.45%。测量得到的kQ与TG - 51协议值之间的最大偏差为0.8%。基于三个能量下的20个电离室,测量值与TG - 51值之间的总体均方根偏差为0.41%。当在计算中考虑1 mm厚的聚甲基丙烯酸甲酯(PMMA)防水套的影响时,最大偏差为1.1%,测量值与计算值之间的总体均方根偏差为0.48%。当使用TPR10(20)指定射束,并且将测量值与使用经修正的形式体系和数据的TG - 21版本计算得到的kQ值进行比较时,在不考虑套修正的情况下,差异高达1.6%。对于有最多文献数据的NE2571和NE2611A电离室类型,使用%dd(10)x时,在整个测量范围内,所有已发表的数据分别显示出0.4%和0.6%的离散度,而当kQ值表示为TPR10(20)的函数时,两个电离室的离散度均高达1.1%。对于PR06 - C电离室,无法确定对束质指定量的明显偏好。当将我们的kQ测量值和计算值的差异与基于相同基础计算但以复合转换因子CQ表示的空气比释动能协议分析进行比较时,我们观察到,使用吸收剂量校准和计算得到的kQ值的系统比基于空气比释动能校准并结合计算得到的CQ的系统更准确(均方根偏差分别为0.48%和0.67%)。

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