• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

年龄对大鼠单侧肾切除术后肾脏增生的影响。

Effect of age on kidney hyperplasia in the rat after unilateral nephrectomy.

作者信息

Soukupová M, Hnĕvkovský P, Najbrt J

出版信息

Adv Exp Med Biol. 1975;53:297-305. doi: 10.1007/978-1-4757-0731-1_24.

DOI:10.1007/978-1-4757-0731-1_24
PMID:1119340
Abstract

The absolute weight of the rat's kidney increases from 3 weeks to 3 months and from 3 months to 12 months. The relative weight decreases. The number of cells freed from the kidney by trypsinization increases. (2) After nephrectomy, the kidney weight increases in all age groups. The increase is mery high in the youngest rats, lower but still significant in the 3 month old rats and still lower in the 12 month old rats. The number of cells freed from the kidney after nephrectomy is again very high in the young and 3 month old rats, but very low in the 12 month old rats. In these animals, the cell number is lower after nephrectomy than before, and a greater vulnerability of the cells is suggested as the cause of this phenomenon.

摘要

大鼠肾脏的绝对重量从3周龄到3月龄以及从3月龄到12月龄均增加。相对重量则下降。通过胰蛋白酶消化从肾脏中释放出的细胞数量增加。(2)肾切除术后,所有年龄组的肾脏重量均增加。在最年幼的大鼠中增加幅度非常高,在3月龄大鼠中较低但仍显著,在12月龄大鼠中更低。肾切除术后从肾脏中释放出的细胞数量在年幼和3月龄大鼠中同样非常高,但在12月龄大鼠中非常低。在这些动物中,肾切除术后的细胞数量比术前低,提示细胞的更大脆弱性是这种现象的原因。

相似文献

1
Effect of age on kidney hyperplasia in the rat after unilateral nephrectomy.年龄对大鼠单侧肾切除术后肾脏增生的影响。
Adv Exp Med Biol. 1975;53:297-305. doi: 10.1007/978-1-4757-0731-1_24.
2
Effect of age on kidney hyperplasia in the rat during cold acclimation.年龄对大鼠冷适应过程中肾脏增生的影响。
Adv Exp Med Biol. 1975;53:307-14. doi: 10.1007/978-1-4757-0731-1_25.
3
Compensatory renal growth after unilateral nephrectomy in the new-born rat.新生大鼠单侧肾切除术后的代偿性肾生长
J Physiol. 1973 Jan;228(1):193-202. doi: 10.1113/jphysiol.1973.sp010081.
4
[Effect of age on the rate of renal hypertrophy after unilateral nephrectomy in rats].
Rev Invest Clin. 1969 Jul-Sep;21(3):275-86.
5
Influence of cyclosporine A on adaptive hypertrophy after unilateral nephrectomy in the rat.
Clin Nephrol. 1986;25 Suppl 1:S144-7.
6
[Apoptosis in the early stage of compensatory renal growth following uninephrectomy in the young and old rats].[青年和老年大鼠单侧肾切除术后代偿性肾生长早期的细胞凋亡]
Zhonghua Yi Xue Za Zhi. 1997 Oct;77(10):742-4.
7
Cyclophosphamide and inhibition of renal compensatory hypertrophy.
Braz J Med Biol Res. 1985;18(4):533-9.
8
Age-dependent characteristics of compensatory renal growth.代偿性肾生长的年龄依赖性特征。
Kidney Int. 1975 Jul;8(1):21-6. doi: 10.1038/ki.1975.72.
9
Influence of age on the compensatory response in growth and function to unilateral nephrectomy.年龄对单侧肾切除术后生长和功能代偿反应的影响。
Yale J Biol Med. 1974 Dec;47(4):218-26.
10
NTP Toxicology and Carcinogenesis Studies of 1-Amino-2,4-Dibromoanthraquinone (CAS No. 81-49-2) in F344/N Rats and B6C3F1 Mice (Feed Studies).1-氨基-2,4-二溴蒽醌(CAS编号:81-49-2)在F344/N大鼠和B6C3F1小鼠中的NTP毒理学与致癌性研究(饲料喂养研究)
Natl Toxicol Program Tech Rep Ser. 1996 Aug;383:1-370.

引用本文的文献

1
Unilateral Nephrectomy Stimulates ERK and Is Associated With Enhanced Na Transport.单侧肾切除刺激细胞外信号调节激酶(ERK)并与钠转运增强相关。
Front Physiol. 2021 Feb 3;12:583453. doi: 10.3389/fphys.2021.583453. eCollection 2021.