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[Gene therapy and tissue engineering in nephrology and renal transplantation].

作者信息

Imai E, Takenaka M, Ito T, Isaka Y, Moriyama T, Hori M

机构信息

Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine.

出版信息

Nihon Rinsho. 2001 Jan;59(1):65-71.

PMID:11197863
Abstract

Human genome project will be completed in 2003 and we will soon obtain the information of the whole DNA sequence of the human genome. This should affect the therapy of progressive renal diseases since we have no effective remedy to cure the renal diseases. Gene therapy, renal engineering and generation of new drug can be achieved by using the information of human genome. In this context, we described our recent endeavors concerning the gene therapy of transplant kidney, seeking the renal stem cells and reprogramming factors, and exploring genes related to renal fibrosis. Completion of bioinformatics, can facilitate the above post-genome project.

摘要

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