Kjellstrom T, Smartt P
New Zealand Environmental and Occupational Health Research Centre (NEOH), Department of Community Health, University of Auckland, Auckland.
N Z Med J. 2000 Nov 24;113(1122):485-90.
To examine the incidence and mortality patterns for malignant mesothelioma and pleural cancer in New Zealand between 1962-1996, and relate these to past use of asbestos.
Data concerning cases of mesothelioma 1962-1996, deaths from pleural and lung cancers 1974-1996, and data on imports of raw asbestos and asbestos products were obtained from government registers and publications. Time trends were analysed using different models.
Mesothelioma incidence rates have increased progressively in New Zealand since the 1960s, and reached 25 per million for men in 1995. The increase follows an exponential model departing from a crude 'background rate' of 1-2 per million in 1984, and is particularly steep in males 50 to 60 years of age. The incidence is expected to double by 2010.
New Zealand has entered an unrivalled period of occupational cancer deaths resulting from past workplace exposure to airborne asbestos fibres. The steep rise in mesothelioma incidence is likely to be accompanied by increases in other asbestos related diseases such as lung cancer. The unique causal association between mesothelioma and asbestos may be used to monitor changes in the public health impact of these exposures. The notification by medical practitioners of all potential asbestos related conditions/exposures to the Occupational Safety and Health (OSH) service is of great importance.
研究1962年至1996年间新西兰恶性间皮瘤和胸膜癌的发病率及死亡率模式,并将其与过去石棉的使用情况相关联。
从政府登记册和出版物中获取1962年至1996年间间皮瘤病例、1974年至1996年间胸膜癌和肺癌死亡数据以及原石棉和石棉产品进口数据。使用不同模型分析时间趋势。
自20世纪60年代以来,新西兰间皮瘤发病率呈逐步上升趋势,1995年男性发病率达到每百万25例。这种增长遵循指数模型,从1984年每百万1至2例的粗略“背景率”开始偏离,在50至60岁男性中尤为陡峭。预计到2010年发病率将翻倍。
由于过去工作场所接触空气中的石棉纤维,新西兰已进入职业性癌症死亡的空前时期。间皮瘤发病率的急剧上升可能伴随着其他与石棉相关疾病(如肺癌)的增加。间皮瘤与石棉之间独特的因果关系可用于监测这些接触对公众健康影响的变化。医生向职业安全与健康(OSH)服务部门通报所有潜在的与石棉相关的病症/接触情况非常重要。