Balz J, Minton J P
Ann Surg. 1975 Jan;181(1):126-8. doi: 10.1097/00000658-197501000-00026.
Three cases of postsplenectomy mesenteric thrombosis, two associated with thrombocytosis, are presented. Experience has shown that persistent thrombocytosis, accompanied by abnormal platelet function, is not a benign condition and may be associated with thrombosis. When encountered, postsplenectomy thrombocytosis of greater than 800,000 per mm-3 must be evaluated by platelet function studies and anticoagulation begun. Post-prandial cramping abdominal pain may be an early symptom of thrombosis, demanding immediate anticoagulation. Low-dose heparin, ASA, and dipyridamole are three of the more commonly used treatment modalities. Small bowel resection is indicated if thrombosis occurs.
本文报告了三例脾切除术后肠系膜血栓形成的病例，其中两例伴有血小板增多症。经验表明，持续性血小板增多症伴有异常的血小板功能并非良性状况，可能与血栓形成有关。当遇到脾切除术后血小板计数大于每立方毫米80万的情况时，必须通过血小板功能研究进行评估，并开始抗凝治疗。餐后腹部绞痛可能是血栓形成的早期症状，需要立即进行抗凝治疗。低剂量肝素、阿司匹林和双嘧达莫是三种较为常用的治疗方式。如果发生血栓形成，则需要进行小肠切除术。
