Noda M, Komatsu H, Inoue S, Sano H
Department of Operative Dentistry, Hokkaido University School of Dentistry, Sapporo, Japan.
J Endod. 2000 Apr;26(4):221-4. doi: 10.1097/00004770-200004000-00005.
Intracanal exudates in persistent endodontic cases were sampled for detecting bacteria using a preculture method, and the antibiotic susceptibility of the bacteria identified was examined. Twelve species were recovered from 15 cases. The species most commonly detected were alpha-Streptococcus and Enterococcus. The results of the antibiotic susceptibility tests revealed that Enterococcus was highly resistant to antibiotics tested, especially to cephalosporin products. Enterococcus is known as one of the bacteria that show multidrug resistance. In cases of prolonged endodontic treatment, a specific antibiotic prescription would play an important role for efficient treatment. Collecting data about antibiotic susceptibility could be helpful. Identification, however, take approximately 2 wk and a further study to develop the method that rapidly informs us about the antibiotic susceptibility that might be needed.
采用预培养方法对持续性牙髓病病例的根管内渗出物进行细菌采样，并检测所鉴定细菌的抗生素敏感性。从15例病例中分离出12种细菌。最常检测到的菌种是α-链球菌和肠球菌。抗生素敏感性测试结果显示，肠球菌对所测试的抗生素具有高度抗性，尤其是对头孢菌素类产品。肠球菌是已知的具有多重耐药性的细菌之一。在牙髓病延长治疗的病例中，特定的抗生素处方对有效治疗将起到重要作用。收集抗生素敏感性数据可能会有所帮助。然而，鉴定大约需要2周时间，可能还需要进一步研究来开发能够快速告知我们抗生素敏感性的方法。
