Metzger Z, Marian-Kfir V, Tamse A
Departments of Oral Biology and Restorative Dentistry, Alpha Omega Research Labora
J Endod. 2000 Jul;26(7):385-8. doi: 10.1097/00004770-200007000-00001.
The putative hazardous nature of chloroform and xylene implies that safer substitutes should be considered. Standard cylindrical gutta-percha samples were immersed in Hemo-De, a xylene substitute, for 60 s at 37 degrees C. Weight loss of a sample, after drying, was used as a measure of its solubility. Master and accessory cone gutta-percha of three brands were compared. The highest solubility of all kinds of gutta-percha was in chloroform, which served as a positive control. The average solubility of all samples in xylene and Hemo-De was 61% and 52% of that in chloroform, respectively. DMS gutta-percha was more soluble than of Hygienic and DeTrey. Master cone gutta-percha of all brands was more soluble than that of their accessory cones. These results indicate that (a) large differences exist in the solubility of gutta-percha and (b) Hemo-De dissolved gutta-percha in a range similar to that of xylene and may be considered as a potential substitute for this organic solvent.
氯仿和二甲苯公认的危险性意味着应考虑更安全的替代品。将标准圆柱形牙胶样本在37摄氏度下于二甲苯替代品Hemo-De中浸泡60秒。样本干燥后的重量损失用作其溶解度的衡量指标。比较了三个品牌的主尖和辅尖牙胶。各类牙胶在氯仿中的溶解度最高，氯仿用作阳性对照。所有样本在二甲苯和Hemo-De中的平均溶解度分别为其在氯仿中溶解度的61%和52%。DMS牙胶比Hygienic和DeTrey的牙胶更易溶解。所有品牌的主尖牙胶比其辅尖牙胶更易溶解。这些结果表明：（a）牙胶的溶解度存在很大差异；（b）Hemo-De溶解牙胶的程度与二甲苯相似，可被视为这种有机溶剂的潜在替代品。
