Chutich M J, Kaminski E J, Miller D A, Lautenschlager E P
Naval Dental Center, Jacksonville, FL, USA.
J Endod. 1998 Apr;24(4):213-6. doi: 10.1016/S0099-2399(98)80098-8.
Three randomly assigned groups of single-canaled extracted teeth obturated with gutta-percha were retreated using controlled application of one of three organic solvents: chloroform, xylene, or halothane. Two additional groups of teeth served as positive and negative controls. Residual volume of solvent expressed through the apical foramen during retreatment was determined by the difference of pretreatment and posttreatment weights of hermetically sealed receptacles attached to the root surface of the teeth. Results indicate that the amount of solvent that has been determined to have leached out through the apical foramen is several orders of magnitude below the permissible toxic dose. Thus, it is proposed that the use of any of the aforementioned solvents used in the retreatment of root canals would pose negligible risk to the patient.
将三组随机分配的、用牙胶充填的单根管离体牙，分别使用三种有机溶剂之一（氯仿、二甲苯或氟烷）进行控制性再治疗。另外两组牙齿作为阳性和阴性对照。再治疗期间通过根尖孔排出的溶剂残留量，由附着在牙根表面的密封容器在治疗前和治疗后的重量差来确定。结果表明，经测定通过根尖孔渗出的溶剂量比允许的中毒剂量低几个数量级。因此，建议在根管再治疗中使用上述任何一种溶剂，对患者造成的风险都可忽略不计。
