Yeung C K, Smith R C, Hill G L
Gastroenterology. 1979 Oct;77(4 Pt 1):652-7.
Measurements of changes in body fat, protein, and water were carried out on two comparable groups of 14 ill surgical patients each over 2-wk period during which one group received an elemental diet (nonprotein energy source was 67% carbohydrate and 33% fat) and the other a course of intravenous nutrition (nonprotein energy source was 100% carbohydrate). The patients fed with the elemental diet had no significant changes in body weight, fat, protein, water, or plasma proteins over the study period, and although the patients fed intravenously also had no changes in body protein or plasma proteins, there was an average gain of 3.2 kg of body weight. This weight gain was mainly extracellular water. It is concluded that the administration of the elemental diet by continuous infusion was comparable to intravenous nutrition in maintaining body protein in these very ill patients and had the advantage of being cheaper and easier to manage. The problem of extracellular water accumulation seen in the patients fed intravenously was not present in the patients who received the elemental diet.
对两组各有14名外科重症患者进行了为期两周的身体脂肪、蛋白质和水分变化测量。在此期间,一组接受要素饮食(非蛋白质能量来源为67%碳水化合物和33%脂肪),另一组接受一个疗程的静脉营养(非蛋白质能量来源为100%碳水化合物)。在研究期间,接受要素饮食的患者体重、脂肪、蛋白质、水分或血浆蛋白均无显著变化,尽管接受静脉营养的患者身体蛋白质或血浆蛋白也无变化,但体重平均增加了3.2千克。这种体重增加主要是细胞外液。得出的结论是,在这些重症患者中,持续输注要素饮食在维持身体蛋白质方面与静脉营养相当,并且具有成本更低、更易于管理的优势。接受静脉营养的患者出现的细胞外液蓄积问题在接受要素饮食的患者中并未出现。