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[间质性肺疾病中支气管肺泡灌洗(BAL)材料用于细胞免疫学检查的最佳制备原则]

[Principles of optimal preparation of material from bronchoalveolar lavage (BAL)for cytoimmunologic examinations in interstitial lung diseases ].

作者信息

Kopiński P, Chłap Z, Owsiński J, Soja J, Stankiewicz Z, Biernat-Silczuk M, Czarnobilska E, Czunko P

机构信息

Katedra Patofizjologii Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie.

出版信息

Przegl Lek. 2000;57(9):489-92.

Abstract

In this paper we considered the value of correctly performed bronchoalveolar lavage (BAL) in diagnosis of interstitial lung diseases and in assessment of the activity of pathological process. We indicated the conditions of exact interpretation of the results of BAL cytoimmunological examination, i.e. fine standard handling of BAL material, including its collection, elaboration and choice of lavage site, as well as regarding external (e.g. cigarette smoking) and internal additional factors. We described the influence of BAL fluid recovery and of the method of staining on obtained results. We emphasized routinely performed BAL to be the valuable diagnostic and research tool in pulmonology however, the method may have limited usefulness and unnecessarily burden the patient, if technical guidelines are not observed.

摘要

在本文中,我们探讨了正确实施支气管肺泡灌洗(BAL)在间质性肺疾病诊断及病理过程活动评估中的价值。我们指出了对BAL细胞免疫检查结果进行准确解读的条件,即对BAL材料的精细规范处理,包括其采集、处理及灌洗部位的选择,以及外部(如吸烟)和内部其他因素。我们描述了BAL液回收率及染色方法对所得结果的影响。我们强调,常规进行的BAL是肺病学中有价值的诊断和研究工具,然而,如果不遵守技术指南,该方法可能有用性有限且给患者带来不必要的负担。

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