Freeman T R, Stewart M, Birtwhistle R, Fisher D C
Can J Public Health. 2000 Nov-Dec;91(6):426-30. doi: 10.1007/BF03404822.
The present study set out to determine the validity of the information and the feasibility of using health diaries to monitor vaccine adverse events. Mothers of children about to receive DPT vaccine were asked to keep a diary of their child’s health and their doctors were randomized into one of three groups: 1) a close follow-up (CFG); 2) a telephone follow-up (TFG); or 3) a mail follow-up group (MFG). Diary return rates were good at 98.8%, 82.5%, and 86.2% for the CFG, TFG, and MFG groups respectively. Agreement between the parent and nurse on the existence of common symptoms was high, varying from 89.9% to 98.7%; redness and swelling was high at 78.5% and 96.2% respectively; and axillary temperatures was lower from 71.6% up. This study found that health diaries were a valid and complete method for monitoring the most common types of vaccine-related illness, with the possible exception of body temperature.
本研究旨在确定信息的有效性以及使用健康日记监测疫苗不良事件的可行性。即将接种白百破疫苗的儿童的母亲被要求记录孩子的健康状况，她们的医生被随机分为三组之一：1）密切随访组（CFG）；2）电话随访组（TFG）；或3）邮件随访组（MFG）。CFG组、TFG组和MFG组的日记回收率分别为98.8%、82.5%和86.2%，情况良好。家长和护士在常见症状是否存在方面的一致性很高，从89.9%到98.7%不等；发红和肿胀的一致性分别为78.5%和96.2%；腋窝温度的一致性较低，为71.6%及以上。本研究发现，健康日记是监测最常见类型的疫苗相关疾病的有效且完整的方法，但体温可能除外。
