Zambrino C A, Balottin U, Ferrari-Ginevra O, D'Arrigo S, Degrate A, Santoro A, Lanzi G
Department of Child Neuropsychiatry, IRCCS C. Mondino Institute of Neurology, University of Pavia, Via Palestro, 3-27100 Pavia, Italy.
Funct Neurol. 2000;15 Suppl 3:106-15.
We evaluate clinical characteristics of headache in a group of subjects > 12 years to assess the sensitivity and specificity of the IHS criteria. We consider whether age at onset may influence the clinical features. We used a semi-structured questionnaire to examine 136 patients consecutively referred to our division. We considered the following subdiagnoses: IHS 1.1, 1.2, 1.7, 2.1, 2.2, 2.3. Migrainous disorders were found to be more common than non-migrainous headaches. A definite diagnosis was established in 68.1% of the migrainous group and in 86.6% of the tension-type headache group. Unilateral location, severe intensity of pain, the presence of nausea, vomiting, phonophobia and photophobia were features which differed between migrainous and non-migrainous subjects. No difference was found regarding aggravation of the headache by physical activity. On the basis of the criterion duration of attacks < 2 hours, IHS 1.7 was found to differ significantly from other migraine types. With the exception of the presence of vomiting in migrainous patients, the age at onset was not found to be a factor influencing the characteristics of the headache. Diagnostic criteria for migraine were highly specific but poorly sensitive, and those for tension-type headaches highly sensitive but less specific. The sensitivity/specificity of the IHS criteria in adolescent migraine can be influenced by the heterogeneity of the clinical characteristics. In fact, the intensity, the location and the quality of pain were similar to those found in childhood migraine, while the concomitant symptoms were less frequent than in childhood and in adult migraine. Further studies are needed to define the degree of severity of the clinical features in adolescent headache and to address the question of the validity of the IHS criteria.
我们评估了一组12岁以上受试者头痛的临床特征,以评估国际头痛协会(IHS)标准的敏感性和特异性。我们考虑发病年龄是否可能影响临床特征。我们使用半结构化问卷对连续转诊至我科的136例患者进行了检查。我们考虑了以下亚诊断:IHS 1.1、1.2、1.7、2.1、2.2、2.3。发现偏头痛性疾病比非偏头痛性头痛更常见。偏头痛组中68.1%的患者和紧张型头痛组中86.6%的患者确诊。单侧发作部位、重度疼痛、恶心、呕吐、畏声和畏光等症状在偏头痛和非偏头痛患者中有所不同。未发现体力活动会加重头痛。根据发作持续时间<2小时的标准,发现IHS 1.7与其他偏头痛类型有显著差异。除偏头痛患者存在呕吐外,未发现发病年龄是影响头痛特征的因素。偏头痛的诊断标准特异性高但敏感性低,紧张型头痛的诊断标准敏感性高但特异性低。IHS标准在青少年偏头痛中的敏感性/特异性可能受临床特征异质性的影响。事实上,疼痛的强度、部位和性质与儿童偏头痛相似,而伴随症状比儿童和成人偏头痛中少见。需要进一步研究来确定青少年头痛临床特征的严重程度,并解决IHS标准的有效性问题。