Karli Necdet, Akgöz Semra, Zarifoğlu Mehmet, Akiş Nalan, Erer Sevda
University of Uludag, School of Medicine, Department of Neurology, Bursa, Turkey.
Headache. 2006 Mar;46(3):399-412. doi: 10.1111/j.1526-4610.2006.00372.x.
Adolescent headaches, particularly migraine, might present with different features from adult headaches. The objectives of this study were to investigate the characteristics of tension-type headache and migraine, to find the sensitivity and specificity of the diagnostic criteria of the IHS classification according to age and gender.
A multistep, stratified, cluster sampling method was used for subject selection. The estimated sample size was 2387. The study was conducted in two phases: the questionnaire and the face to face interview phases. During the semistructured interview, a clinical diagnosis has been made and clinical characteristics have been recorded.
All headaches fulfilled the criteria of duration. The most common feature of migraine was moderate to severe (92.4%), pulsating pain (79.2%). For ETTH, bilateral localization (91.3%) and mild to moderate pain intensity (90.6%) were the most common features. Younger adolescents showed mixed headache characteristics. Highest sensitivities for migraine were duration (100%), moderate to severe pain (92.4%), and pulsating quality of pain (79.2%). Vomiting, trigger factors food and alcohol had a high specificity for migraine.
Our data strongly support continuum hypothesis. In early adolescence headaches might present with mixed headache characteristics. Age and gender have some influence on headache characteristics, particularly on migraine. The sensitivity and specificity of case definition criteria of ICHD-2 for adolescent migraine is moderate and need to be reconsidered.
青少年头痛,尤其是偏头痛,可能具有与成人头痛不同的特征。本研究的目的是调查紧张型头痛和偏头痛的特点,根据年龄和性别找出国际头痛疾病分类(IHS)诊断标准的敏感性和特异性。
采用多步骤、分层、整群抽样方法选择研究对象。估计样本量为2387。研究分两个阶段进行:问卷调查阶段和面对面访谈阶段。在半结构式访谈过程中,进行了临床诊断并记录了临床特征。
所有头痛均符合持续时间标准。偏头痛最常见的特征是中重度(92.4%)、搏动性疼痛(79.2%)。对于发作性紧张型头痛,双侧疼痛部位(91.3%)和轻至中度疼痛强度(90.6%)是最常见的特征。青少年早期表现出混合性头痛特征。偏头痛最高的敏感性在于持续时间(100%)、中重度疼痛(92.4%)和搏动性疼痛性质(79.2%)。呕吐、食物和酒精等触发因素对偏头痛具有较高的特异性。
我们的数据有力地支持了连续性假说。在青春期早期,头痛可能表现出混合性头痛特征。年龄和性别对头痛特征有一定影响,尤其是对偏头痛。国际头痛疾病分类第二版(ICHD-2)中青少年偏头痛病例定义标准的敏感性和特异性中等,需要重新考虑。