Lannoo E, Colardyn F, Jannes C, de Soete G
Department of Rehabilitation, University of Gent, Belgium.
Brain Inj. 2001 Jan;15(1):1-13.
Neuropsychological outcome and recovery of a group of 91 patients with moderate-to-severe head injuries were prospectively investigated over a 2 year period, with evaluations at acute hospital discharge at 6 months and 2 years post-injury. A group of 39 trauma patients with injuries to parts of the body other than the head were used as controls. The head injured group performed significantly worse than the control group at baseline, 6 months and 2 years post-injury. Significant improvement was found during the first 6 months, but also between 6 months and 2 years post-injury. Trauma controls also performed significantly better at 6 months post-injury compared to baseline. Differential practice effects between groups cause difficulties in determining recovery. Within the head injured group, three distinct recovery groups were identified varying as a function of coma-length and coma-duration. The first group is comparable with the trauma controls. The other two groups demonstrate significant neuropsychological impairments at baseline, with one group showing a marked improvement over the 2 year period, and the other group showing only small improvement over this time period.
对一组91例中重度颅脑损伤患者的神经心理学结果及恢复情况进行了为期2年的前瞻性研究，在急性出院时、伤后6个月和2年进行评估。选取39例身体其他部位受伤的创伤患者作为对照组。颅脑损伤组在基线、伤后6个月和2年时的表现明显比对照组差。在伤后的前6个月以及6个月至2年期间均发现有显著改善。创伤对照组在伤后6个月时的表现也明显优于基线水平。组间不同的练习效应给恢复情况的判定带来了困难。在颅脑损伤组中，根据昏迷时长和昏迷持续时间确定了三个不同的恢复组。第一组与创伤对照组相当。另外两组在基线时表现出明显的神经心理学损伤，其中一组在2年期间有显著改善，而另一组在此期间仅有微小改善。
